Table 4 VDR polymorphisms and exacerbation frequency
SNP | Genotype | Frequent exacerbators (n = 28) | Infrequent exacerbators (n = 68) | Chi squared P value |
|---|---|---|---|---|
Rs1544410 | BB | 3 (10.7%) | 15 (22.1%) | Â |
BsmI | Bb | 12 (42.9%) | 26 (38.2%) | 0.43 |
| Â | Bb | 13 (46.4%) | 27 (39.7%) | Â |
HWE p value | Â | 0.93 | 0.08 | Â |
|  |  | (n = 26) | (n = 66) |  |
Rs731236 | TT | 10 (38.5%) | 24 (36.4%) | Â |
TaqI | Tt | 13 (50%) | 29 (43.9%) | 0.64 |
| Â | Tt | 3 (11.5%) | 13 (19.7%) | Â |
HWE p value | Â | 0.69 | 0.43 | Â |
|  |  | (n = 28) | (n = 68) |  |
Rs2228570 | FF | 10 (35.7%) | 21 (30.9%) | Â |
FokI | Ff | 14 (50.0%) | 38 (55.9%) | 0.87 |
| Â | Ff | 4 (14.3%) | 9 (13.2%) | Â |
HWE p value | Â | 0.80 | 0.21 | Â |