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Table 1 Median (IQR) temperature (°C)

From: Low-dose endotoxin inhalation in healthy volunteers - a challenge model for early clinical drug development

 

Body **

Breath*

LPS 1

pre

36.2 (0.8)

33.8 (1.1)

3 h post

36.2 (0.9)

33.6 (0.5)

6 h post

36.7 (0.3)##

33.9 (0.5)

LPS 2

pre

36.4 (0.5)

33.7 (0.4)

3 h post

36.2 (0.6)

33.7 (0.3)

6 h post

36.6 (0.6)§

34.0 (0.5)

LPS Tx

pre

36.3 (0.6)

33.8 (0.5)

3 h post

36.3 (0.5)

34.2 (0.7)

 

6 h post

36.7 (0.3)##

33.9 (0.6)

  1. ** p < 0.01, *p < 0.05 for repeated measures ANOVA with visit (LPS1, 2, Tx) as a factor. Newman-Keuls post-hoc test: ## p < 0.01, § p = 0.08 compared with “pre”-challenge.