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Figure 2 | BMC Pulmonary Medicine

Figure 2

From: Oral intake of phenylbutyrate with or without vitamin D3upregulates the cathelicidin LL-37 in human macrophages: a dose finding study for treatment of tuberculosis

Figure 2

Viable Mtb CFU count in Monocyte derived macrophages (MDM). MDM from different group of volunteers were incubated with Mtb H37Rv strain for 2 h, after that extracellular bacteria were removed and cultured for 3 days, cells were lysed and plated for variable colony (CFU) count. Group-I: 250 mg PB b.d. + 5000 IU vitamin D3 o.d.; Group-II: 500 mg PB b.d. + 5000 IU vitamin D3 o.d.; Group-III: 1000 mg PB b.d. + 5000 IU vitamin D3 o.d.; Group-IV: 500 mg PB b.d.; Group-V: 5000 IU vitamin D3 o.d.. PB: Phenylbutyrate. b.d.: twice daily. o.d. : once daily. The straight horizontal line indicates means. Data were analyzed by two-way (treatment and time) repeated measures ANOVA. * p < 0.05, and *** p < 0.001.

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