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Table 4 Outcomes (repeat COPD exacerbation and mortality) in the three months following COPD exacerbation by FEV1

From: Variability of antibiotic prescribing in patients with chronic obstructive pulmonary disease exacerbations: a cohort study

Outcome

FEV1 severity

Number of events (numerator)

Incidence rate per 10,000 person years

Age and sex adjusted hazard ratio

Repeat COPD exacerbation

Mild

123

12.2 (10.2–14.5)

1.00

 

Moderate

256

10.9 (9.6–12.3)

0.90 (0.72–1.11)

 

Severe

287

14.6 (13.0–16.4)

1.22 (0.99–1.51)

 

Very severe

129

17.8 (15.0–21.2)

1.51 (1.18–1.94)

 

Unknown

103

12.4 (10.2–15.0)

1.01 (0.78–1.32)

All cause mortality

Mild

75

4.9 (3.9–6.1)

1.00

 

Moderate

103

2.9 (2.4–3.5)

0.60 (0.45–0.81)

 

Severe

192

6.4 (5.5–7.4)

1.26 (0.97–1.65)

 

Very severe

107

9.6 (8.0–11.6)

2.14 (1.59–2.88)

 

Unknown

166

13.2 (11.3–15.3)

2.23 (1.69–2.93)