Clinical profile of recurrent community-acquired pneumonia in children

BMC Pulmonary Medicine

Table 2 Predisposing factors associated with CAP recurrences in children with rCAP and controls, and corresponding odds ratios (ORs) with 95% confidence intervals (95% CI)

	Patients with rCAP		Healthy controls		Comparison between groups	OR (95% CI)^§
	(n = 146)	%	(n = 145)	%	p°°
Predisposing factor
Heart disease
Yes	3	2.1	0	0	0.25	-
No	143	97.9	145	100.0
Oro-motor incoordination/swal-lowing dysfunction
Yes	4	2.7	0	0	0.12	-
No	142	97.3	145	100.0
Primary ciliary dyskinesia
Yes	1	0.7	0	0	1.00	-
No	145	99.3	145	100.0
Primary or acquired immunodeficiency
Yes	2	1.4	0	0	0.50	-
No	144	98.6	145	100.0
GERD
Yes	31	21.2	20	13.8	0.69	1.33 (0.64-2.80)
No	115	78.8	125	86.2		1^§§
Overweight/obesity
BMI SD <1	112	76.7	119	82.1	0.76	1^§§
BMI SD ≥1	34	23.3	26	17.9		1.34 (0.58-1.97)
Wheezing
Yes	113	77.4	20	13.8	<0.001	32.00 (10.14-100.96)
No	33	22.6	125	86.2		1^§§
Chronic rhinosinusitis with post-nasal drip
Yes	105	71.9	6	4.1	<0.001	59.33 (24.48-144.97)
No	41	28.1	139	95.9		1^§§
Middle lobe syndrome
Yes	44	30.1	0	0
No	102	69.9	145	100.0	<0.001	-
Recurrent upper respiratory tract infections
Yes	99	67.8	29	20.0	<0.001	6.75 (3.68-12.37)
No	47	32.2	116	80.0		1^§§
Atopy/allergy
Yes	75	51.4	17	11.7	<0.001	7.44 (3.71-14.93)
No	71	48.6	128	88.3		1^§§
Asthma
Yes	46	31.5	8	5.5	<0.001	10.50 (3.77-29.28)
No	100	68.5	137	94.5		1^§§

CI: confidence interval; BMI SD: body mass index standard deviation; GERD: gastroesophageal reflux diseae; OR: odds ratio. °°Chi-squared or Fisher’s test, as appropriate; rCAP: recurrent community-acquired pneumonia. ^§ORs from conditional logistic regression model, stratified by gender and age.^§§reference category.

ISSN: 1471-2466