Gene | SNP | Protein | Allele change | Location | Association |
---|---|---|---|---|---|
NOS1 | rs41279104 | Neuronal NOS | C = > T | Promoter for exon 1c | Reduced gene expression [12] |
NOS2 | rs8078340 | Inducible NOS | G = > A | Promoter region | Decreased DNA-protein complex [13] |
NOS3 | rs1800779 | Endothelial NOS | A = > G | Intronic | Lower FEV1 % predicted in COPD patients [14] |