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Table 3 Description of the polymorphisms studied

From: Nitric oxide synthase polymorphisms, gene expression and lung function in chronic obstructive pulmonary disease

Gene SNP Protein Allele change Location Association
NOS1 rs41279104 Neuronal NOS C = > T Promoter for exon 1c Reduced gene expression [12]
NOS2 rs8078340 Inducible NOS G = > A Promoter region Decreased DNA-protein complex [13]
NOS3 rs1800779 Endothelial NOS A = > G Intronic Lower FEV1 % predicted in COPD patients [14]