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Table 5 Linear regression model explaining fractional exhaled nitric oxide (FeNO) given as ln FeNO at 11 years of age in 105 children hospitalized for bronchiolitis and 89 children in an age matched control group, all children analysed together

From: Exhaled nitric oxide is related to atopy, but not asthma in adolescents with bronchiolitis in infancy

  Unadjusted models Fully adjusted model (N = 190) Final model (N = 190)
Risk factors B* 95% CI P-value B* 95% CI P-value B* 95% CI P-value
Hospitalization for bronchiolitis −0.200 −0.408, 0.008 0.059 −0.088 −0.276, 0.101 0.359  
Male gender −0.131 −0.342, 0.080 0.223       
Age at follow up (months) 0.009 −0.006, 0.024 0.257       
Height (cm) 0.021 0.007, 0.034 0.002 0.025 0.008, 0.042 0.005 0.027 0.015, 0.038 <0.001
Weight (kg) 0.014 0.004, 0.025 0.009 0.001 −0.012, 0.014 0.849    
Atopy 0.736 0.539, 0.934 <0.001 0.757 0.562, 0.951 <0.001 0.773 0.583, 0.962 <0.001
Current asthma 0.035 −0.243, 0.313 0.805       
Ln DRS 0.053 −0.003, 0.108 0.062 0.056 0.008, 0.105 0.023 0.051 0.004, 0.097 0.034
FEV1% 0.006 −0.004, 0.016 0.269       
FEF25-75% 0.001 −0.003, 0.006 0.597       
Use of inhaled steroids preceding 12 months 0.200 −0.169, 0.568 0.287       
  1. No interactions were found between current asthma and atopy, atopy and DRS, atopy and hospitalization for bronchiolitis or DRS and hospitalization for bronchiolitis.
  2. *Regression coefficient, represents the amount of change of ln NO induced by a change of 1 unit of the explanatory variable.
  3. CI, confidence interval; DRS, dose response slope; FEV1%, forced expiratory volume in first second as percentage of predicted; FEF25-75%, forced expiratory flow between 25-75% of the forced vital capacity.
  4. Bold values indicate significance at the 0.05 level.