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Table 3 Univariate analysis of potential predictors of mortality

From: Plasma YKL-40 and all-cause mortality in patients with chronic obstructive pulmonary disease

 

Hazard rate

95% Confidence interval

p-value

High vs. normal plasma YKL-40**

1.42

1.15 – 1.75

0.001

Age*

1.04

1.03 – 1.06

<0.001

Neutrophils†

1.05

1.01 – 1.09

0.006

Charlson score index > 2

1.21

0.94 – 1.54

0.14

Moderate COPD‡

Ref. value

Ref. value

-

Severe COPD‡

1.38

1.06 – 1.77

0.014

Very severe COPD‡

1.94

1.45 – 2.60

<0.001

Smoking at baseline

1.10

0.90 – 1.35

0.36

BMI < 20

1.17

0.91 – 1.50

0.21

Pack years > 40

1.29

1.05 – 1.58

0.014

  1. *Estimated hazard ratio associated with an increment of one year.
  2. **Patients were dichotomized according to the 75th percentile of plasma YKL-40 in age-matched healthy subjects (30).
  3. †Estimated hazard ratio associated with an increment of 1 * 109 cells/L.
  4. ‡Moderate COPD (79–50 FEV1 % predicted), severe COPD (30–50 FEV1 % predicted) [32], and very severe COPD (< 30 FEV1 % predicted).
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BMC Pulmonary Medicine

ISSN: 1471-2466

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