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Table 4 Multivariate proportional hazards Cox regression of prognostic markers for mortality

From: Plasma YKL-40 and all-cause mortality in patients with chronic obstructive pulmonary disease

 

Adjusted hazard ratio

95% Confidence interval

p-value

High vs. normal plasma YKL-40**

1.38

1.11 - 1.72

0.004

Age*

1.05

1.03 - 1.06

<0.0001

Neutrophils†

1.05

1.01- 1.08

0.01

Moderate COPD‡

Ref. Value

Ref. Value

Ref. Value

Severe COPD‡

1.35

1.03 - 1.76

0.03

Very severe COPD‡

2.19

1.60 - 2.99

<0.0001

Pack years > 40

1.38

1.11- 1.71

0.003

  1. *Estimated hazard ratio associated with an increment of one year.
  2. **Patients were dichotomized according to the 75th percentile of plasma YKL-40 in age-matched healthy subjects (30).
  3. †Estimated hazard ratio associated with an increment of 1 * 109 cells/L.
  4. ‡Moderate COPD (79–50 FEV1 % predicted), Severe COPD (30–50 FEV1 % predicted) [32].
  5. and Very Severe COPD (< 30 FEV1 % predicted).
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BMC Pulmonary Medicine

ISSN: 1471-2466

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