Table 1 Demographics of patients with COPD
| Â | All subjects (n=153) | GOLD II (n=101) | GOLD III/IV (n=52) | p value |
|---|---|---|---|---|
Age (years) | 63.2 (8.2) | 63.4 (8.7) | 63.1 (7.2) | 0.86 |
Male, n (%) | 83 (55%) | 56 (56%) | 27 (52%) | 0.63 |
Race, Caucasian, n (%) | 140 (92%) | 92 (91%) | 49 (94%) | 0.67 |
BMI (kg/m2) | 26.9 (4.8) | 27.6 (4.7) | 25.5 (4.7) | 0.01 |
Current smoker, n (%) | 77 (49%) | 50 (50%) | 25 (48%) | 0.82 |
Total pack-years | 56.5 (29.4) | 56.2 (27) | 57.1 (33.8) | 0.87 |
FEV1 (% predicted) | 55.4 (15.2) | 64.8 (7.5) | 37.4 (8.4) | <0.001 |
FEV1 (L) | 1.62 (0.6) | 1.9 (0.52) | 1.08 (0.29) | <0.001 |
FEV1/FVC | 0.55 (0.11) | 0.59 (0.08) | 0.53 (0.09) | <0.001 |
Coronary artery disease, n (%) | 46 (30%) | 32 (32%) | 14 (27%) | 0.52 |
Diabetes mellitus,n (%) | 45 (30%) | 30 (30%) | 15 (29%) | 0.88 |
Cerebrovascular disease, n (%) | 6 (4%) | 5 (5%) | 1 (2%) | 0.67 |
Peripheral vascular disease, n (%) | 13 (9%) | 11 (11%) | 2 (4%) | 0.22 |
Cardiovascular disease, n (%) | 53 (35%) | 39 (39%) | 14 (27%) | 0.16 |
Systolic BP | 127.6 (17.1) | 128.8 (17) | 125.3 (17.3) | 0.24 |
Temperature (°C) | 36.5 (0.3) | 36.5 (0.3) | 36.5 (0.4) | 0.50 |
TAC | 3556.8 (6156.9) | 3923.2 (7919.4) | 2852.0 (3616.1) | 0.31 |
CAC | 741.2 (1061.4) | 789.6 (1094.9) | 648.1 (997.3) | 0.44 |
aPWV (m/s) | 9.98 (2.85) | 10.14 (2.88) | 9.69 (2.79) | 0.37 |
% CT emphysema | 8.93 (11.39) | 5.63 (7.32) | 15.28 (14.76) | <0.001 |
Total cholesterol (mmol/L) | 4.81 (1.1) | 4.73 (1.12) | 4.94 (1.04) | 0.24 |
LDL cholesterol (mmol/L) | 2.59 (0.97) | 2.53 (0.92) | 2.71 (1.07) | 0.28 |
HDL cholesterol (mmol/L) | 1.45 (0.53) | 1.38 (0.49) | 1.59 (0.58) | 0.03 |
hsCRP (mg/L) | 4.59 (7.0) | 5.05 (8.16) | 3.70 (3.73) | 0.27 |
Plasma glucose (mmol/L) | 5.85 (1.4) | 6.05 (1.53) | 5.44 (0.95) | 0.01 |