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Table 1 Demographics of patients with COPD

From: Determinants of arterial stiffness in COPD

  All subjects (n=153) GOLD II (n=101) GOLD III/IV (n=52) p value
Age (years) 63.2 (8.2) 63.4 (8.7) 63.1 (7.2) 0.86
Male, n (%) 83 (55%) 56 (56%) 27 (52%) 0.63
Race, Caucasian, n (%) 140 (92%) 92 (91%) 49 (94%) 0.67
BMI (kg/m2) 26.9 (4.8) 27.6 (4.7) 25.5 (4.7) 0.01
Current smoker, n (%) 77 (49%) 50 (50%) 25 (48%) 0.82
Total pack-years 56.5 (29.4) 56.2 (27) 57.1 (33.8) 0.87
FEV1 (% predicted) 55.4 (15.2) 64.8 (7.5) 37.4 (8.4) <0.001
FEV1 (L) 1.62 (0.6) 1.9 (0.52) 1.08 (0.29) <0.001
FEV1/FVC 0.55 (0.11) 0.59 (0.08) 0.53 (0.09) <0.001
Coronary artery disease, n (%) 46 (30%) 32 (32%) 14 (27%) 0.52
Diabetes mellitus,n (%) 45 (30%) 30 (30%) 15 (29%) 0.88
Cerebrovascular disease, n (%) 6 (4%) 5 (5%) 1 (2%) 0.67
Peripheral vascular disease, n (%) 13 (9%) 11 (11%) 2 (4%) 0.22
Cardiovascular disease, n (%) 53 (35%) 39 (39%) 14 (27%) 0.16
Systolic BP 127.6 (17.1) 128.8 (17) 125.3 (17.3) 0.24
Temperature (°C) 36.5 (0.3) 36.5 (0.3) 36.5 (0.4) 0.50
TAC 3556.8 (6156.9) 3923.2 (7919.4) 2852.0 (3616.1) 0.31
CAC 741.2 (1061.4) 789.6 (1094.9) 648.1 (997.3) 0.44
aPWV (m/s) 9.98 (2.85) 10.14 (2.88) 9.69 (2.79) 0.37
% CT emphysema 8.93 (11.39) 5.63 (7.32) 15.28 (14.76) <0.001
Total cholesterol (mmol/L) 4.81 (1.1) 4.73 (1.12) 4.94 (1.04) 0.24
LDL cholesterol (mmol/L) 2.59 (0.97) 2.53 (0.92) 2.71 (1.07) 0.28
HDL cholesterol (mmol/L) 1.45 (0.53) 1.38 (0.49) 1.59 (0.58) 0.03
hsCRP (mg/L) 4.59 (7.0) 5.05 (8.16) 3.70 (3.73) 0.27
Plasma glucose (mmol/L) 5.85 (1.4) 6.05 (1.53) 5.44 (0.95) 0.01
  1. All values expressed as mean (standard deviation) unless otherwise specified.
  2. P value for comparisons between GOLD II and GOLD III/IV.
  3. Definition of abbreviations: GOLD = Global initiative for Obstructive Lung Disease; BMI = body mass index; FEV1 = forced expiratory volume in the first 1 second; FVC = forced vital capacity; TAC = thoracic aortic calcification; CAC = coronary arterial calcification; aPWV = aortic pulse wave velocity; CT = computed tomography; LDL = low density lipoprotein; HDL = high density lipoprotein; hsCRP = high sensitivity C-reactive protein.