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Table 5 Comparison of clinical, radiological, and pathological features among CPFE groups with or without thick-walled cystic lesions

From: An autopsy study of combined pulmonary fibrosis and emphysema: correlations among clinical, radiological, and pathological features

 

CPFE

 
 

With TWCLs

Without TWCLs

 

(n = 15)

(n = 7)

p-value

Age, years

   

Median

73

68

0.7852

Range

60–86

64–95

 

Smoking history, pack years

   

Median

60

80

0.2954

Range

20–150

30–200

 

Extent of emphysema

   

0-25%

1 (6.7%)

3 (42.9%)

0.077

25-50%

4 (26.7%)

3 (42.9%)

0.387

>50%

10 (66.7%)

1 (14.3%)

0.032

Pulmonary function test

   

VC

2.67 ± 0.63

2.05 ± 0.64

0.1672

%VC

87.37 ± 17.0

64.6 ± 23.7

0.0947

FEV1

2.09 ± 0.51

1.67 ± 0.32

0.1813

FEV1/FVC,%

74.6 ± 7.44

80.5 ± 11.2

0.3142

DLCO

6.93 ± 3.85

5.77 ± 4.56

0.733

%DLCO

39.5 ± 16.7

31.2 ± 21.5

0.5721

DLCO/VA

2.05 ± 0.8

2.48 ± 1.49

0.6024

%DLCO/VA

46.0 ± 17.4

56.3 ± 34.9

0.5778

EsPAP

51.5 ± 22.5

46.67 ± 9.07

0.7379

Distribution of TWCLs

   

Upper lobe

12 (80%)

-

-

Lower lobe

11 (73.3%)

-

-

Primary lesion of lung cancer

   

Emphysema

2 (14.3%)

0

0.455

Fibrosis

5 (35.7%)

3 (60%)

0.51

TWCLs

4 (26.7%)

-

-

Others

3 (20%)

2 (40%)

0.523

Diffuse alveolar damage

3 (20%)

3 (42.9%)

0.267

  1. TWCLs, thick-walled cystic lesions.
  2. CPFE, combined pulmonary fibrosis and emphysema.
  3. EsPAP, estimated systolic pulmonary artery pressure.