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Table 1 Patient demographics and characteristics (safety population) and lung function at baseline (intent-to-treat [ITT] population)

From: Efficacy and safety of fluticasone furoate 100 μg and 200 μg once daily in the treatment of moderate-severe asthma in adults and adolescents: a 24-week randomised study

 

FF 100 μg

FF 200 μg

Total

Patient demographics (safety population)

N

119

119

238

Age, years

46.6 (15.4)

45.1 (15.8)

45.9 (15.6)

(range)

(12–76)

(12–70)

(12–76)

Female sex, n (%)

81 (68)

79 (66)

160 (67)

White race, n (%)

101 (85)

100 (84)

201 (84)

Patient characteristics (safety population)

Duration of asthma, years

20.1 (15.9)

21.5 (15.0)

20.8 (15.4)

≥ 1 exacerbation in prior 12 months, n (%)

73 (61)

67 (56)

140 (59)

Lung function parameters (ITT population)

N

108*

111

219*

Percent reversibility FEV1 at screening,%

30.6 (16.1)

33.9 (20.6)

32.3 (18.5)

Pre-dose FEV1 at baseline, L

2.04 (0.67)

2.08 (0.65)

2.06 (0.66)

Percent predicted FEV1 at baseline,%

68.4 (14.0)

67.8 (13.3)

68.1 (13.6)

  1. All data are mean (SD) unless otherwise stated.
  2. *Baseline lung function data available for 107 patients in the FF 100 μg group (218 in total).
  3. FF = fluticasone furoate; NA = not applicable; SD = standard deviation.