Figure 2

Seasonal variation of serum KL-6 concentrations in various ILD. (A) The ratio of maximum concentrations of summer and winter serum KL-6 concentrations (Smax/Wmax) in various ILD. Seasonal changes in serum KL-6 concentrations in a patient with House-HP who had a specific IgG antibody against Trichosporon asahii (B) and in a patient with Bird-HP related to feather pillow use (C). The duration when the patient did not refer to the hospital was shown by dot line in Figure 2C. Corticosteroids were not administered to either patient because of patients’ refusal. The open and closed squares over the figure indicate the summer and winter seasons, respectively. (D) Variations of maximal and minimal serum KL-6 concentrations (Kmax-Kmin) in patients with acute HP and chronic HP.