BMC Pulmonary Medicine

Table 3 Relationship of 6-minute walk test outcomes to cardiopulmonary exercise test and demographics

From: Cardiorespiratory responses to 6-minute walk test in interstitial lung disease: not always a submaximal test

	All cohort (n =47)			IPF subgroup (n = 27)			Non-IPF subgroup (n = 20)
	6MWD, meters	6MWT VO₂peak, L.min⁻¹	6MWT Nadir SpO₂	6MWD, meters	6MWT VO₂peak, L.min⁻¹	6MWT Nadir SpO₂	6MWD, meters	6MWT VO₂peak, L.min⁻¹	6MWT Nadir SpO₂
CPET VO₂peak, L.min⁻¹	0.71**	0.71**	0.28	0.74**	0.79**	0.24	0.55*	0.77**	0.35
CPET VCO₂peak, L.min⁻¹	0.77**	0.74**	0.19	0.77**	0.78**	0.14	0.69**	0.80**	0.35
CPET VEpeak, L.min⁻¹	0.36*	0.21	−0.03	0.31	0.24	−0.37	0.46*	0.71**	0.29
CPET Peak Work, Watts	0.77**	0.38*	0.35*	0.86**	0.64**	0.15	0.73**	0.62**	0.48*
CPET NadirSpO₂, %	0.21	0.13	0.76**	0.25	0.29	0.85**	0.05	0.03	0.61**
Age, years	−0.42**	−0.14	−0.23	−0.42*	−0.41*	0.04	−0.47*	−0.09	−0.35
Height, cm	0.09	−0.20	0.10	0.10	0.06	−0.15	0.15	0.51*	0.35
FVC%pred	0.22	−0.12	0.50**	0.13	0.04	0.49*	0.37	0.04	0.52*
TLCO%pred	0.34*	0.14	0.60**	0.28	0.35	0.64**	0.39	0.27	0.47*
RVSP, mmHg	−0.46*	−0.33	−0.48	−0.49	−0.43	−0.47	−0.16	0.37	0.73

Data are Pearson’s r. *p <0.05, **p < 0.01 for relationship between variables. CPET = cardiopulmonary exercise test, VO₂peak = peak oxygen uptake, 6MWT = six-minute walk test, 6MWD = six-minute walk distance, NadirSpO₂ = lowest oxyhaemoglobin saturation, VO₂ – oxygen uptake, VCO₂ - carbon dioxide production, VE – ventilation, FVC – forced vital capacity, TLCO – diffusing capacity for carbon monoxide, RVSP – right ventricular systolic pressure on trans-thoracic echocardiogram.

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