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Table 3 Clinical characteristics of community acquired pneumonia patients with different etiology

From: Respiratory virus is a real pathogen in immunocompetent community-acquired pneumonia: comparing to influenza like illness and volunteer controls

 

Flu A

Flu B

ADV

PIV-1

PIV-3

Rhv

HCoV OC43

Dual-virus

Virus positive

Virus negative

P values**

Cases

24

5

2

2

10

2

2

5

52

97

 

Demographic data

           

Age (Median [IQR], yrs)

74(32–80)

47(36–73)

21(20–23)

72(65–78)

63(40–70)

72(66–77)

71(67–74)

59(45–65)

62(32–79)

60(36–75)

0.961

Male/Female

15/9

3/2

1/1

2/0

3/7

2/0

0/2

3/1

29/23

55/42

0.913

Sick contact*

5(20.8)

1(20.0)

0

0

1(10.0)

0

0

2(40.0)

9(17.3)

10(10.3)

0.222

Current smoking

3(12.5)

1(20.0)

0

0

2(20.0)

0

0

1(25.0)

7(13.5)

19(19.6)

0.348

Clinical symptoms

           

Fever ≥ 39°C

14(58.3)

3(60.0)

2(100)

1(50.0)

6(60.0)

1(50.0)

0

4(80.0)

31(59.6)

49(50.5)

0.288

Headache

8(33.3)

3(60.0)

1(50.0)

0

9(90.0)

1(50.0)

0

3(60.0)

25(48.1)

47(48.5)

0.965

Mylgia

10(41.7)

3(60.0)

1(50.0)

0

0

0

0

3(60.0)

17(32.7)

33(34.0)

0.870

Fatigue

14(58.3)

4(80.0)

1(50.0)

1(50.0)

8(80.0)

1(50.0)

0

3(60.0)

32(61.5)

46(47.4)

0.100

Coryza

10(41.7)

2(40.0)

1(50.0)

0

4(40.0)

1(50.0)

0

3(60.0)

21(40.4)

28(28.9)

0.154

Sore throat

10(41.7)

2(40.0)

2(100.0)

0

4(40.0)

2(100)

1(50.0)

4(80.0)

25(48.1)

30(30.9)

0.038

Dry cough

2(8.3)

1(20.0)

1(50.0)

0

0

0

0

0

4(7.7)

9(9.3)

0.982

Purulent sputum

12(50.0)

2(40.0)

1(50.0)

1(50.0)

5(50.0)

1(50.0)

0

4(80.0)

26(50.0)

49(50.5)

0.777

Hemoptysis

2(8.3)

0

0

0

2(20.0)

0

0

0

4(7.7)

3(3.1)

0.391

Chest tightness or pain

6(25.0)

0

0

0

1(10.0)

2(100)

1(50.0)

0

10(19.2)

22(22.7)

0.625

Dyspnea

12(50.0)

3(60.0)

0

1(50.0)

4(40.0)

0

1(50.0)

0

21(40.4)

33(34.0)

0.441

Gastrointestinal symptoms

5(20.8)

1(20.0)

0

0

1(10.0)

1(50.0)

0

1(20)

9(17.3)

15(15.5)

0.770

Laboratory results

           

Leukocytosis

8(33.3)

0

1(50.0)

1(50.0)

1(10.0)

1(50.0)

1(50.0)

0

13(25.0)

43(44.8)

0.020

Neutrophilia§

8(33.3)

0

1(50.0)

1(50.0)

1(10.0)

1(50.0)

1(50.0)

0

13(25.0)

39(40.6)

0.063

Lymphopenia

6(25.0)

0

0

1(50.0)

1(10.0)

0

0

0

7(13.5)

9(9.4)

0.432

ESR > 20 mm/h||

9(81.8)

NA

0

1(100.0)

4(80.0)

1(100)

1(100)

2(66.6)

18(78.3)

45(83.3)

0.597

PaO2 < 80 mmHg||

10(41.7)

2(40.0)

1(50.0)

1(50.0)

3(75.0)

2(100)

1(50.0)

1(50.0)

21(67.7)

26(61.9)

0.607

  1. Note: *All data were showed as numbers (%) unless otherwise specified. Leukocytosis was defined as leukocyte count >10 × 109/L. §Neutrophilia was defined as neutrophil count >8 × 109/L. Lymphopenia was defined as lymphocyte count <0.8 × 109/L. ||Data were available only in some patients. **Comparisons were made between virus positive patients and virus negative patients by non-parametric Kruskal-Wallis test for quantitative characteristics and Fisher’s exact or Chi-square test for categorical variables, respectively. NA: Data is not available. ESR: erythrocyte sedimentation rate. Gastrointestinal symptoms included nausea, vomiting, diarrhea, abdominal pain, and abdominal distention.