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Table 2 Association between TSH and parameters of spirometry and cardiopulmonary exercise testing

From: Serum thyroid-stimulating hormone levels are not associated with exercise capacity and lung function parameters in two population-based studies

 

Model 1

Model 2

Model 3

TSH full range

TSH < 0.3#

TSH > =3#

TSH in the reference range

β (95%-CI)

β (95%-CI)

β (95%-CI)

β (95%-CI)

FEV 1 ; l

-0.01 (-0.04; 0.01)

0.06 (-0.06; 0.17)

-0.06 (-0.14; 0.02)

0.01 (-0.03; 0.04)

FVC; l

-0.003 (-0.034; 0.028)

0.03 (-0.10; 0.17)

-0.08 (-0.21; 0.04)

0.02 (-0.03; 0.06)

FEV 1 /FVC; %

-0.35* (-0.65; -0.06)

-0.06 (-1.23; 1.12)

-0.78 (-2.02; 0.47)

-0.48* (-0.91; -0.04)

peakVO 2 ; ml/min

1.2 (-18.1; 20.4)

19.2 (-46.4; 84.8)

3.0 (-98.5; 104.5)

12.9 (-15.4; 41.3)

VO 2 @AT; ml/min

-4.7 (-14.8; 5.5)

14.0 (-19.3; 47.4)

-9.3 (-52.0; 33.5)

-4.2 (-18.2; 9.9)

O 2 HR; ml/beat

-0.11* (-0.22; -0.01)

0.33 (-0.14; 0.81)

-0.31 (-0.88; 0.26)

-0.08 (-0.25; 0.08)

V E vs. VCO 2 slope

0.11 (-0.06; 0.29)

-0.44 (-1.08; 0.19)

0.05 (-0.69; 0.79)

0.21 (-0.05; 0.46)

Maximum power; watt

1.3 (-0.1; 2.7)

0.1 (-5.7; 6.0)

-0.4 (-11.1; 10.3)

1.9 (-0.1; 3.9)

Exercise duration; minutes

0.02 (-0.08; 0.12)

0.02 (-0.33; 0.37)

-0.16 (-0.62; 0.29)

0.07 (-0.07; 0.20)

  1. Median regression adjusted for age, sex, body mass index, beta blocker intake, smoking status, physical activity, study and time between examinations; *p < 0.05; #Reference: TSH in the reference range.