Figure 1
From: Clinical significance of mTOR, ZEB1, ROCK1 expression in lung tissues of pulmonary fibrosis patients
Representative lung tissue sections of usual interstitial pneumonia patients exemplifying the two principal grades of fibrosis and expression levels observed with the different markers. Low-power images showing grade of fibrosis (A, grade 1 fibrosis; B, grade 7 fibrosis; hematoxylin and eosin staining, 40× magnification) The mTOR and ZEB1 expressed in hyperplastic alveolar epithelial cells and some mesenchymal cells from fibrotic areas (C, mTOR intermediate; D, mTOR strong; E, ZEB1 intermediate; F, ZEB1 strong). ROCK1 expressed in hyperplastic alveolar epithelial cells, mesenchymal cells, macrophages and lymphocytes of the UIP patients (G, ROCK1 intermediate; H, ROCK1 strong). (C-H); immunohistochemical staining, brown color, 400× magnification.