BMC Pulmonary Medicine

Table 1 Localization of inhibin subunit antibody immunoreactivity in human control (Ctrl) and idiopathic pulmonary fibrosis (IPF) lung

From: Upregulation of activin-B and follistatin in pulmonary fibrosis – a translational study using human biopsies and a specific inhibitor in mouse fibrosis models

Patient	Inhibin ß_A			Inhibin ß_B			Follistatin
Localization	(H)AEC	BE	MΦ	(H)AEC	BE	MΦ	(H)AEC	BE	MΦ
Ctrl1	-	-	++	-	-	-	-	+++	++
Ctrl2	-	+	+	-	+	+	-	-	++
Ctrl3	-	+	+	-	+	+	-	+++	+++
Ctrl4	-	-	-	-	+	+	-	++	++
Ctrl5	-	-	-	-	-	-	-	++	++
IPF/UIP1	++	++	++	+	+	-	+++	+++	+++
IPF/UIP2	+++	++	+++	+	+	-	++	++	++
IPF/UIP3	-	-	-	-	+	-	+++	+++	+++
IPF/UIP4	+++	+++	+++	+	-	-	++	++	+++
IPF/UIP5	++	++	++	+	++	-	+++	+++	+++

The histopathological finding of IPF is usual interstitial pneumonia (UIP). (H)AEC, (hyperplastic) alveolar epithelial cells; BE, bronchial epithelial cells; MΦ, macrophages.

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