Table 5 Association of haplotypes with pulmonary function in the analysis adjusted for age, gender and smoking
From: Genetic variants in ADAM33 are associated with airway inflammation and lung function in COPD
| Â | Â | Â | Â | P-value | |||||
|---|---|---|---|---|---|---|---|---|---|
T2 | T1 | S2 | Q-1 | Percent-predicted FEV1 | FEV1/FVC | Percent-predicted TLCO | Percent-predicted FEV1 | FEV1/FVC | Percent-predicted TLCO |
| Â | Â | Â | Â | Disease | Normal | ||||
G | G | G | G | 0.0247 | – | 1.04e-005 | – | – | – |
G | G | C | G | – | – | 0.000205 | – | – | – |
A | A | G | A | – | – | 0.000368 | – | – | – |
A | A | G | G | 0.00176 | 0.000154 | 1.67e-007 | – | – | – |
A | A | C | A | – | – | 0.000224 | – | – | – |
G | A | G | A | – | – | – | 0.005447 | – | – |
G | G | C | A | 0.000234 | 0.000272 | 1.22e-005 | – | – | – |
A | G | G | A | – | – | 0.0392 | – | – | – |
G | G | G | A | 8.68e-005 | 0.00209 | 6.98e-016 | – | – | – |
G | A | G | G | – | – | 0.00319 | – | – | – |
A | A | C | G | 0.0154 | 0.0465 | 0.0014 | – | – | – |