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Figure 4 | BMC Pulmonary Medicine

Figure 4

From: Cisplatin sensitivity is enhanced in non-small cell lung cancer cells by regulating epithelial-mesenchymal transition through inhibition of eukaryotic translation initiation factor 5A2

Figure 4

GC7 regulated EMT in NSCLC cells via inhibition of eIF5A-2. (A–B) Western blotting and immunofluorescence showed no significant changes in expression levels of EMT marker proteins, E-cadherin and vimentin, are observed in A549 cells after GC7 treatmen. (C-D) Western blotting and immunofluorescence showed significant changes in expression levels of EMT marker proteins, E-cadherin and vimentin, are observed in NCI-H1299 cells after GC7 treatment. (E) The migration and (F) invasion capabilities are weaker in NCI-H1299 cells after GC7 treatment.

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BMC Pulmonary Medicine

ISSN: 1471-2466

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