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Table 2 Variables not paired among cases and controls

From: COPD Assessment Test (CAT) score as a predictor of major depression among subjects with chronic obstructive pulmonary disease and mild hypoxemia: a case–control study

 

All subjects

Cases

Control group

 
 

n = 60

n = 30

n = 30

p

Male gender, n (%)

36 (60)

15 (50)

21 (70)

0.11

BMI, kg/m2

24.9 ± 5.0

24.5 ± 4.6

25.3 ± 5.5

0.54

Neck circumference, cm

36.4 ± 4.8

35.6 ± 4.8

37.3 ± 4.7

0.22

Systolic blood pressure, mmHg

120 (20)

125 (20)

120 (20)

0.61

Diastolic blood pressure, mmHg

74.5 ± 8.5

74.3 ± 6.3

74.7 ± 10.4

0.88

Hypertension treatment, n (%)

34 (56.7)

18 (60)

16 (53.3)

0.60

Smoking intensity (pack years)

48.5 (33)

46.5 (38.4)

48.5 (32)

0.83

Smoking status

Current smoker

15 (25)

9 (30)

6 (20)

 

n (%)

Former smoker

40 (66.7)

17 (56.7)

23 (76.7)

0.21

 

Never smoked

5 (8.3)

4 (13.3)

1 (3.3)

 

COPD Classification

GOLD A

6 (10)

3 (10)

3 (10)

0.09

n (%)

GOLD B

8 (13.3)

7 (23.3)

1 (3.3)

 

GOLD C

1 (1.7)

0 (0)

1 (3.3)

 

GOLD D

45 (75)

20 (66.7)

25 (83.3)

Pos-Bd FVC (liters)

2.52 ± 0.8

2.46 ± 0.8

2.57 ± 0.9

0.59

Pos-Bd FEV1 (liters)

1.31 ± 0.6

1.33 ± 0.6

1.29 ± 0.6

0.78

Pos-Bd FEV1/FVC (%)

75.5 ± 18.4

53 ± 12.1

49.8 ± 12.1

0.31

PaO2, mmHg

71.7 ± 8.9

71.3 ± 8.0

72.1 ± 9.7

0.73

PaCO2, mmHg

34.9 ± 5.0

34.1 ± 5.8

35.7 ± 4.2

0.24

Oxygen saturation, gasometry (%)

93.8 ± 2.0

93.9 ± 2.1

93.7 ± 1.9

0.71

LV ejection fraction (%)

69.5 (8)

70 (10)

69 (6)

0.93

LV systolic dysfunction, n (%)

2 (3.3)

2 (6.7)

0 (0)

0.49

LV diastolic dysfunction, n (%)

43 (71.7)

22 (73.3)

21 (70)

0.77

Pulmonary hypertension , n (%)

3 (5)

1 (3.3)

2 (6.7)

0.70

Normal sPAP, n (%)

28 (46.7)

13 (43.3)

15 (50)

Undetermined sPAP, n (%)

29 (48.3)

16 (53.4)

13 (43.3)

Beck Depression Inventory (0–63)

15.4 ± 10.4

22.3 ± 9.6

8.6 ± 5.4

<0.0001*

COPD Assessment Test (0–40)

17.1 ± 7.1

19.8 ± 7.3

14.3 ± 5.8

0.002*

  1. Data are presented as mean ± SD, n (%) or median (interquartile range). The Socioeconomic score was assessed by the questionnaire of the Brazilian Association of Research Companies (range 0–40). LV systolic dysfunction definition: left ventricular ejection fraction (LVEF) ≤40%. sPAP: systolic pulmonary artery pressure. Pulmonary hypertension: sPAP > 40. Undetermined sPAP: patients without tricuspid regurgitant flow.