Figure 2

Relationship between adverse event outcomes and volume treated. Graphical representation of volume treated during the VAPOR trial to demonstrate the risk of having a SAE increases as the volume treated per session increases. Each patient is represented by a bar along the horizontal axis. Volume treated during the VAPOR trial is on the vertical axis. To promote safety, volume treated per session is now capped at 1700 ml. The SAE rate is 54% for treatments above 1700 ml and is much smaller at 10% for treatments larger than 1700 ml.