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Table 3 Fragmentation of SP-A and SP-D in the bronchoalveolar lavage fluid of idiopathic pulmonary fibrosis patients

From: Distinct compartmentalization of SP-A and SP-D in the vasculature and lungs of patients with idiopathic pulmonary fibrosis

 

Sup-2

Ppt

 

SP-A (%)

2.1 (0.9 – 4.4)

97.9 (95.6 – 99.1)

P < 0.001

SP-D (%)

52.4 (48.4 – 79.3)

47.6 (20.7 – 51.6)

P = 0.011

Total Phospholipid (%)

0.0 (0.0 – 8.3)

100.0 (91.7 – 100.0)

P < 0.001

  1. Bronchoalveolar lavage fluid was centrifuged (1,000 g) to remove cell components (Sup-1), and Sup-1 was centrifuged again (33,000 g) into a supernatant (Sup-2) and precipitate (Ppt). The percentage of fragmentation of SP-A, SP-D and phospholipids in each segment was examined. The data are presented as median (interquartile range). SP-A, surfactant protein A; SP-D, surfactant protein D.