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Table 3 Fragmentation of SP-A and SP-D in the bronchoalveolar lavage fluid of idiopathic pulmonary fibrosis patients

From: Distinct compartmentalization of SP-A and SP-D in the vasculature and lungs of patients with idiopathic pulmonary fibrosis

  Sup-2 Ppt  
SP-A (%) 2.1 (0.9 – 4.4) 97.9 (95.6 – 99.1) P < 0.001
SP-D (%) 52.4 (48.4 – 79.3) 47.6 (20.7 – 51.6) P = 0.011
Total Phospholipid (%) 0.0 (0.0 – 8.3) 100.0 (91.7 – 100.0) P < 0.001
  1. Bronchoalveolar lavage fluid was centrifuged (1,000 g) to remove cell components (Sup-1), and Sup-1 was centrifuged again (33,000 g) into a supernatant (Sup-2) and precipitate (Ppt). The percentage of fragmentation of SP-A, SP-D and phospholipids in each segment was examined. The data are presented as median (interquartile range). SP-A, surfactant protein A; SP-D, surfactant protein D.