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Table 3 Association between glycaemia, HOMA-IR, metabolic syndrome (MS) and ventilatory function*†

From: Ventilatory function and cardiovascular disease risk factors: a cross-sectional study in young adults

Metabolic outcomes

Level compared

FEV1(L) β-coefficient (95% CI)

FVC (L) β-coefficient (95% CI)

Whole sample (n = 970)

Fasting glycaemia (tertile)

1

0

0

2

0.01 (-0.06 to 0.07)

0.01 (-0.06 to 0.08)

3

0.04 (-0.02 to 0.11)

0.03 (-0.04 to 0.10)

P value

0.19

0.43

HOMA-IR

Normal

0

0

High

-0.08 (-0.13 to -0.03)

-0.11 (-0.17 to -0.05)

P value

0.004

<0.0001

Metabolic syndrome

Not present

0

0

Present

-0.13 (-0.21 to -0.05)

-0.18 (-0.27 to -0.09)

 

P value

0.001

<0.001

Men (n = 429)

Fasting glycaemia (tertile)

1

0

0

2

-0.01 (-0.12 to 0.09)

-0.001 (-0.13 to 0.12)

3

-0.06 (-0.16 to 0.04)

-0.06 (-0.18 to 0.05)

P value

0.24

0.25

HOMA-IR

Normal

0

0

High

-0.12 (-0.21 to -0.03)

-0.13 (-0.23 to -0.03)

P value

0.007

0.01

Metabolic syndrome

Not present

0

0

Present

-0.18 (-0.32 to -0.05)

-0.20 (-0.35 to -0.04)

 

P value

0.009

0.01

Women (n = 521)

Fasting glycaemia (tertile)

1

0

0

2

-0.002 (-0.06 to 0.06)

-0.03 (-0.07 to 0.06)

3

0.01 (-0.06 to 0.08)

-0.03 (-0.11 to 0.04)

P value

0.80

0.41

HOMA-IR

Normal

0

0

High

-0.03 (-0.09 to 0.04)

-0.07 (-0.14 to -0.004)

P value

0.43

0.04

Metabolic syndrome

Not present

0

0

Present

-0.09 (-0.18 to 0.01)

-0.16 (-0.26 to -0.05)

 

P value

0.08

0.003

  1. (*) Multiple linear regressions adjusted for age, gender (where appropriate), height, weight at birth, educational level, smoking, SES, and BMI; Confidence Interval.
  2. †p-values in bold letters indicate statistical significance.