|
Biomarker
|
Non-sensitized
|
OVA-sensitized
|
N6022 0.1 mg/kg
|
N6022 1 mg/kg
|
|---|
|
Fibrinogen
|
74540.0 ± 5605.7*
|
126250.0 ± 11070.8
|
32240.0 ± 7486.6*
|
68560.0 ± 4251.7*
|
|
Haptoglobin
|
22.0 ±4.3*
|
103.8 ±11.6*
|
43.4 ±13.8*
|
33.8 ±8.4*
|
|
IgA
|
366.2 ± 14.6*
|
236.8 ±10.0
|
347.2 ±14.8*
|
344.2 ±11.3*
|
|
IL-5
|
1.1 ±0.1*
|
2.3 ±0.3*
|
1.2 ±0.2*
|
1.0 ± 0.1*
|
|
IL-18
|
45.4 ±1.6*
|
63.0 ±2.1
|
51.4 ±6.5
|
50.6 ±2.4*
|
- Plasma biomarker levels were determined using a multi-analyte profile of biomarker patterns. Values are the means ± SEM (N = 5) in either μg/mL (Fibrinogen, Haptoglobin, and IgA) or ng/mL (IL-5 and IL-18).
- *p < 0.05 vs. OVA-sensitized, One-way ANOVA, Dunnett’s.
