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Table 2 Biomarker patterns in plasma

From: Pharmacologic inhibition of S-nitrosoglutathione reductase protects against experimental asthma in BALB/c mice through attenuation of both bronchoconstriction and inflammation

Biomarker Non-sensitized OVA-sensitized N6022 0.1 mg/kg N6022 1 mg/kg
Fibrinogen 74540.0 ± 5605.7* 126250.0 ± 11070.8 32240.0 ± 7486.6* 68560.0 ± 4251.7*
Haptoglobin 22.0 ±4.3* 103.8 ±11.6* 43.4 ±13.8* 33.8 ±8.4*
IgA 366.2 ± 14.6* 236.8 ±10.0 347.2 ±14.8* 344.2 ±11.3*
IL-5 1.1 ±0.1* 2.3 ±0.3* 1.2 ±0.2* 1.0 ± 0.1*
IL-18 45.4 ±1.6* 63.0 ±2.1 51.4 ±6.5 50.6 ±2.4*
  1. Plasma biomarker levels were determined using a multi-analyte profile of biomarker patterns. Values are the means ± SEM (N = 5) in either μg/mL (Fibrinogen, Haptoglobin, and IgA) or ng/mL (IL-5 and IL-18).
  2. *p < 0.05 vs. OVA-sensitized, One-way ANOVA, Dunnett’s.