Table 1 Demographics
2006/2007 Complete cohort | 2006/2007 Data for subjects studied in 2012 | 2012 Data | ||||
|---|---|---|---|---|---|---|
Healthy smokers (N = 23) | COPD smokers (N = 24) | Healthy smokers (N = 11) | COPD smokers (N = 13) | Healthy smokers (N = 11) | COPD smokers (N = 13) | |
Female/male | 6/17 | 6/18 | 4/7 | 4/9 | 4/7 | 4/9 |
Age [years]a | 54 (42, 65) | 54 (46, 68) | 56 (51, 61) | 53 (50, 56) | 60 (56, 66) | 58 (55, 61) |
BMI [kg/m2] | 25.4 ± 2.5 | 25.3 ± 3.4 | 25.5 ± 1.8 | 24.4 ± 3.0 | 26.7 ± 3.0 | 25.5 ± 3.9 |
Pack-years & | 34.0 (21.0) | 48.0 (15.5)*** | 32.0 (21.0) | 47.0 (15.0) | 37.5 (16.8) | 50.1 (16.7) |
Cotinine (ng/mL) | 1262 ± 722 | 1561 ± 968 | 1232 ± 548 | 1620 ± 748 | 867 ± 659 | 1585 ± 678 |
FEV1 [L] | 3.8 ± 0.8 | 2.0 ± 0.3*** | 3.5 ± 0.6 | 2.0 ± 0.3 | 3.2 ± 0.5 | 1.5 ± 0.5 |
FEV1 % pred. | 112.5 ± 14.1 | 60.5 ± 6.8*** | 114.9 ± 12.8 | 60.7 ± 5.5 | 109,6 ± 14.2 | 47.3 ± 15.0 |
FVC [L] | 5.1 ± 1.0 | 4.2 ± 0.9** | 4.7 ± 0.9 | 4.3 ± 0.8 | 4.5 ± 0.7 | 3.6 ± 0.8 |
FEV1/FVC [%] | 75.4 ± 5.0 | 48.7 ± 7.4*** | 74.3 ± 5.1 | 48.2 ± 6.7 | 71.1 ± 4.2 | 41.0 ±11.7 |
pO2 [mm Hg] | 82.9 ± 9.7 | 73.3 ± 5.3*** | 81.2 ± 9.2 | 75.1 ± 5.7 | 76.5 ± 7.4 | 69,2 ± 7.6 |