Table 2 Repeatability of hematology data and selected serum proteins
Parameter | Unit | r | ICC | Healthy smokers | COPD smokers | Healthy vs. COPD | 2006/2007 vs. 2012$ | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
2006/2007# | 2012& | All | Healthy | COPD | |||||||
smokers | smokers | ||||||||||
Whole blood | Leukocytes | 109/L | 0.84 | 0.85 | 7.1 (4.8-7.9) | 7.4 (6.8-9.3) | |||||
Neutrophils | (%) | 0.54 | 0.50 | 54.3 (51.4-63.8) | 62.6 (58.4-64.4) | ||||||
Monocytes | (%) | 0.72 | 0.70 | 8.4 (8.2-9.0) | 7.7 (6.9-9.4) | p = 0.03 | |||||
Erythrocytes | 1012/L | 0.79 | 0.78 | 4.8 (4.6-5.0) | 4.8 (4.5-5.0) | ||||||
Thrombocytes | 109/L | 0.86 | 0.86 | 248.0 (208.0-272.0) | 208.0 (176.0-257.0) | ||||||
Anisocytosis | 0.81 | 0.82 | 45.0 (43.0-47.0) | 46.0 (46.0-47.0) | p = 0.014 | ||||||
Hemoglobin | g/dL | 0.80 | 0.81 | 14.8 (14.0-15.1) | 15.0 (14.2-15.7) | ||||||
Hematocrit | % | 0.73 | 0.73 | 44.0 (42.0-44.0) | 44.0 (43.0-47.0) | ||||||
MCH | pg | 0.83 | 0.68 | 30.8 (29.2-31.9) | 31.5 (30.7-32.6) | p < 0.001 | p = 0.03 | p < 0.005 | |||
MCV | 109 μL | 0.91 | 0.91 | 89.1 (87.0-94.8) | 93.0 (91.1-94.4) | p = 0.008 | |||||
Serum | Serum creatinine | mg/dL | 0.88 | 0.71 | 0.9 (0.8-1.0) | 0.8 (0.7-0.9) | p = 0.006 | p = 0.003 | |||
ALP | U/L | 0.86 | 0.78 | 79.0 (65.0-95.0) | 89.0 (70.5-97.5) | ||||||
AST/GOT | U/L | 0.68 | 0.79 | 25.0 (24.0-30.0) | 23.5 (20.5-29.5) | ||||||
ALT/GPT | U/L | 0.67 | 0.58 | 23.0 (21.0-38.0) | 21.5 (18.5-33.5) | ||||||
G-GT | U/L | 0.87 | 0.82 | 27.0 (20.0-30.0) | 42.5 (22.0-56.0) | p = 0.09 | p = 0.05 | p = 0.01 | p = 0.03 | ||
LTB4 | μg/mL | 0.01 | −0.02 | 1.5 (0.9-2.1) | 1.6 (1.2-2.0) | m: p = 0.0051 | nd | nd | nd | ||
A1AT | ng/mL | 0.74 | −0.53 | 767.9 (707.5-844.5) | 870.9 (828.8-906.6) | m: p = 0.014 | p = 0.02 | nd | nd | nd | |
IL6 | pg/mL | 0.25 | −0.34 | 1.6 (1.1-3.4) | 3.2 (2.0-4.0) | p = 0.002 | p = 0.02 | nd | nd | nd | |
VWF | U/mL | 0.69 | 0.67 | 1.3 (1.1-1.6) | 1.8 (1.6-2.0) | p = 0.003 | p = 0.004 | ||||