Table 3 Hospital stay and resource use analysed by clinical outcomes
Resource | Initial antibiotic treatment modification | Comorbidities | Recurrences | Septic shock | ||||
|---|---|---|---|---|---|---|---|---|
With (n = 589) | Without (n = 1,450) | With (n = 1,598) | Without (n = 441) | With (n = 94) | Without (n = 1,945) | With (n = 84) | Without (n = 1,955) | |
Total duration of hospitalization, days, mean (SD) [median] | 16.1 (13.1) [12.0] (n = 581) | 11.1 (8.9) [9.0] (n = 1,397) | 13.3 (11.1) [10.0] (n = 1,555) | 10.0 (7.5) [8.0] (n = 423) | 25.1 (16.9) [19.0] (n = 94) | 11.5 (8.7) [9.0] (n = 1,548) | 21.8 (18.7) [17.0] (n = 83) | 12.2 (9.9) [9.0] (n = 1,895) |
Admitted to ICU at any time, n (%) | 106 (18.0) | 172 (11.9) | 219 (13.7) | 59 (13.4) | 19 (20.2) | 177 (11.4) | 69 (82.1) | 209 (10.7) |
Time in ICU, days, mean (SD) [median] | 11.2 (13.6) [5.0] (n = 90) | 8.5 (10.4) [5.5] (n = 154) | 9.9 (12.5) [6.0] (n = 191) | 8.3 (8.1) [5.0] (n = 53) | 12.9 (17.8) [4.0] (n = 17) | 8.7 (10.7) [5.0] (n = 176) | 13.7 (16.2) [8.5] (n = 54) | 8.3 (9.8) [5.0] (n = 190) |
Blood pressure support during hospitalization, n (%) | ||||||||
Fluid resuscitation | 95 (16.1) | 156 (10.8) | 209 (13.1) | 42 (9.5) | 15 (16.0) | 155 (10.0) | 63 (75.0) | 188 (9.6) |
Vasopressors | 46 (7.8) | 55 (3.8) | 77 (4.8) | 24 (5.4) | 5 (5.3) | 42 (2.7) | 71 (84.5) | 30 (1.5) |
Invasive procedures | 13 (2.2) | 17 (1.2) | 22 (1.4) | 8 (1.8) | 2 (2.1) | 13 (0.8) | 12 (14.3) | 18 (0.9) |
Isolation required, n (%) | 55 (9.3) | 99 (6.8) | 114 (7.1) | 40 (9.1) | 5 (5.3) | 92 (5.9) | 20 (23.8) | 134 (6.9) |
Mechanical ventilation required during hospitalization, n (%) | 114 (19.4) | 166 (11.4) | 232 (14.5) | 48 (10.9) | 10 (10.6) | 149 (9.6) | 68 (81.0) | 212 (10.8) |
Invasive | 61 (10.4) | 78 (5.4) | 108 (6.8) | 31 (7.0) | 4 (4.3) | 56 (3.6) | 60 (71.4) | 79 (4.0) |
Duration, days, mean (SD) [median] | 12.9 (15.8) [8.0] (n = 58) | 8.6 (9.3) [5.0] (n = 75) | 10.9 (13.7) [6.0] (n = 103) | 9.0 (8.1) [8.0] (n = 30) | 21.3 (28.0) [9.5] (n = 4) | 11.1 (9.9) [8.0] (n = 53) | 10.8 (10.5) [8.0] (n = 58) | 10.2 (14.2) [5.0] (n = 75) |
Non-invasive | 68 (11.5) | 98 (6.8) | 146 (9.1) | 20 (4.5) | 8 (8.5) | 102 (6.6) | 20 (23.8) | 146 (7.5) |
Duration, days, mean (SD) [median] | 6.0 (5.4) [4.0] (n = 64) | 4.6 (3.7) [4.0] (n = 91) | 5.3 (4.7) [4.0] (n = 139) | 4.1 (3.4) [3.5] (n = 16) | 3.0 (0.8) [3.0] (n = 8) | 5.6 (4.8) [4.0] (n = 99) | 4.9 (5.1) [3.0] (n = 20) | 5.2 (4.5) [4.0] (n = 135) |
Parenteral nutrition, n (%) | 38 (6.5) | 56 (3.9) | 79 (4.9) | 15 (3.4) | 5 (5.3) | 50 (3.2) | 16 (19.0) | 78 (4.0) |
Duration of parenteral nutrition, days, mean (SD) [median] | 13.4 (14.9) [6.0] (n = 34) | 6.4 (5.2) [5.0] (n = 54) | 9.2 (10.7) [5.0] (n = 73) | 8.4 (10.7) [4.0] (n = 15) | 16.4 (22.9) [8.0] (n = 5) | 8.0 (7.0) [5.0] (n = 46) | 11.5 (13.9) [5.0] (n = 14) | 8.6 (9.9) [5.0] (n = 74) |
Acute renal failure necessitating renal replacement therapy, n (%) | 25 (4.2) | 21 (1.4) | 36 (2.3) | 10 (2.3) | 1 (1.1) | 16 (1.0) | 22 (26.2) | 24 (1.2) |
Duration of renal failure, days, mean (SD) [median] | 8.5 (8.6) [6.0] (n = 19) | 4.3 (8.3) [2.0] (n = 18) | 5.9 (7.4) [3.0] (n = 29) | 8.6 (12.3) [2.5] (n = 8) | 3.0 (-) [3.0] (n = 1) | 6.8 (9.4) [3.5] (n = 14) | 7.1 (8.9) [4.0] (n = 17) | 6.0 (8.5) [3.0] (n = 20) |
Septic shock, n (%) | 40 (6.8) | 44 (3.0) | 61 (3.8) | 23 (5.2) | 4 (4.3) | 34 (2.2) | N/A | N/A |
Home-based care, n (%) | 25 (4.2) | 48 (3.3) | 64 (4.0) | 9 (2.0) | 7 (7.4) | 65 (4.2) | 3 (3.6) | 70 (3.6) |