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Table 1 Patient characteristics

From: Serum heat shock protein 47 levels are elevated in acute interstitial pneumonia

 

Healthy volunteer (N = 19)

COP (N = 12)

NSIP (N = 16)

IPF (N = 19)

AIP (N = 9)

p value

Age (years)

35*

(27-59)

65.5

(38-87)

57.0

(28-74)

64.0

(34-75)

75.0

(53-81)

<0.001

Sex (male/female)

11/8

 

7/5

 

6/10

 

13/6

 

6/3

 

N.S.

Smoking (s/ex/n)

0/0/19

 

2/4/6

 

3/5/8

 

6/5/8

 

5/1/3

 

0.002

P/F ratio (mmHg)

-

 

385.0

(289.5-490.5)

399.3

(343.3-442.4)

389.8

(283.3-491.9)

102.3¶

(59.9-254.8)

<0.001

A-a DO2 (mmHg)

-

 

19.9

(-5.14-46.9)

15.3

(2.6-37.9)

17.1

(-3.5-52.7)

402¶

(58.6-611.4)

<0.001

  1. Data presented as median (range).
  2. N = number of patients; COP = cryptogenic organizing pneumonia; NSIP = nonspecific interstitial pneumonia; IPF = idiopathic pulmonary fibrosis; AIP = acute interstitial pneumonia; N.S. = not significant; s/ex/n = current smoker/ex-smoker/nonsmoker; P/F ratio = PaO2/fraction of inspired oxygen (FiO2) ratio; A-a DO2 = alveolar-arterial difference of oxygen.
  3. *P < 0.01 compared with COP, NSIP, IPF, and AIP.
  4. ¶P < 0.01 compared with COP, NSIP, and IPF.
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BMC Pulmonary Medicine

ISSN: 1471-2466

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