Figure 2

TCR Vβ expansions in CD8 ⁺ -BAL (A) and PBMC (B). Each circle indicates a sample from one patient. Eleven of the patients had one or more expansions (filled circles) of CD8⁺ T cells expressing a particular Vβ gene segment in the BAL fluid. In BAL (A) Vβ2, Vβ7.1, Vβ7.2, Vβ11, Vβ13.2, Vβ13.6, Vβ21.3 and Vβ23 were expressed as T cell expansions in one patient each, Vβ8 and Vβ22 in two patients each and Vβ12 and Vβ16 in three patients. In PBMC (B) Vβ1 and Vβ13.2 were expressed as expansions in on patient each, Vβ11, Vβ12 and Vβ13.1 in two patients each and Vβ16 in four patients. (Definition of T cell expansion was > mean plus two* SD of a cohort of healthy controls subjects).