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Table 1 Participant characteristics

From: High prevalence of altered cardiac repolarization in patients with COPD

  COPD N = 91 Matched controls N = 32 Healthy controls N = 41
Demographics and cardiovascular risk    
Age, y 62 (7.1) 62 (5.9) 30 (8.7)
Male/Female 61/30 24/8 24/17
BMI, kg/m2 27.9 (6.0) 29.2 (4.4) 22.8 (3.1)
Current smokers, N (%) 19 (21) 7 (22) 5 (13)
Pack years of smoking, N 43 (23.7)* 9 (18.2) 1 (5.1)
Arterial hypertension, N (%) 49 (54) 23 (72) 0 (0)
CAD, N (%) 18 (20) 3 (9) 0 (0)
Arrhythmia, N (%) 19 (21) 8 (25) 4 (10)
Diabetes, N (%) 13 (14) 3 (9) 0 (0)
Cholesterol, mmol/l 5.2 (1.1) 4.9 (1.0) 5.1 (1.1)
Pocock risk score, % 2.2 (2.1) 2.1 (0.9) 0.3 (0.3)
Respiratory variables    
FEV1% pred. 45 (22.4)* 104 (16.0) 100 (11.1)
FVC% pred. 77 (18.3)* 108 (14.0) 104 (8.2)
FEV1/FVC,% 45 (15.2)* 78 (5.5) 80 (5.9)
SaO2, kPa 93.8 (3.4) 95.1 (1.3) 98.0 (1.4)
Medication    
Medication affecting QT, N (%) 12 (13) 4 (13) 0 (0)
Beta blockers, N (%) 18 (20) 10 (31) 0 (0)
Antihypertensive medication, N (%) 47 (52) 19 (59) 0 (0)
Anticholinergic medication, N (%) 62 (68)* 0 (0) 0 (0)
Combined inhaled long-acting β-adrenergic and steroid, N (%) 53 (58)* 0 (0) 0 (0)
Statins, N (%) 30 (33) 11 (34) 0 (0)
  1. Values are mean (SD). *p < 0.05 COPD vs. matched controls. p < 0.05 COPD vs. healthy controls. p < 0.05 matched controls vs. healthy controls. BMI: body mass index; CAD: coronary artery disease; FEV1: forced expiration in one second; FVC: forced volume capacity; SaO2: oxygen saturation.