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Table 2 Univariate regression analysis of predictors for QTc in all participants

From: High prevalence of altered cardiac repolarization in patients with COPD

 

β

95% confidence interval

p-value

Cardiovascular risk

   

Age, y

0.30

0.15/0.45

<0.001*

Male/Female

-0.08

-0.23/0.08

0.317

BMI, kg/m2

0.13

-0.02/0.28

0.104

Current smoker, N (%)

-0.01

-0.16/0.15

0.934

Pack years of smoking, N

0.28

0.13/0.44

<0.001*

Pocock risk score, %

0.17

-0.00/0.35

0.054

Respiratory variables

   

FEV1% pred.

-0.30

-0.48/-0.12

0.001*

FVC% pred.

-0.32

-0.50/-0.15

<0.001*

SaO2, %

-0.34

-0.51/-0.17

<0.001*

Medication

   

Medication affecting QT, N (%)

0.13

-0.03/0.28

0.108

Beta blocker, N (%)

0.05

-0.11/0.20

0.558

Combined inhaled long-acting β-adrenergic and steroid, N (%)

0.28

0.13/0.43

<0.001*

Statins, N (%)

0.23

0.07/0.38

0.004*

  1. *p < 0.05; QTc: QT interval corrected for heart rate; BMI: body mass index; FEV1: forced expiration in one second; FVC: forced vital capacity; SaO2: arterial oxygen saturation.