Table 1 Main sociodemographic characteristics at inclusion and clinical profile of COPD patients prescribed with FSC
GPs | N patients (n = 352) | Pulmonologists | N patients (n = 358) | |
|---|---|---|---|---|
Age in years, mean (SD) | 61.6 (11.4) | 352 | 65.3 (11.5) | 358 |
Male, N (%) | 227 (64.5%) | 352 | 269 (75.1%) | 358 |
Professional status, N (%) | 352 | 357 | ||
Working | 122 (34.7%) | 57 (16.0%) | ||
Retired | 186 (52.8%) | 246 (68.9%) | ||
Other | 44 (12.5%) | 54 (15.1%) | ||
BMI (kg/m 2 ), N (%) | 349 | 358 | ||
Underweight (<18) | 10 (2.9%) | 25 (7.0%) | ||
Normal (18–25) | 131 (37.5%) | 138 (38.5%) | ||
Overweight (25–30) | 133 (38.1%) | 121 (33.8%) | ||
Obese (≥ 30) | 75 (21.5%) | 74 (20.7%) | ||
Current smoker, N (%) | 195 (55.4%) | 352 | 127 (35.6%) | 357 |
Pulmonary hypertension, N (%) | 12 (3.5%) | 343 | 32 (9.2%) | 348 |
≥1 cardiovascular comorbidity, N (%) | 116 (33.0%) | 352 | 138 (38.5%) | 358 |
Heart failure | 44 (12.5%) | 43 (12.0%) | ||
Coronary heart disease | 35 (9.9%) | 62 (17.3%) | ||
Peripheral artery disease | 48 (13.6%) | 45 (12.6%) | ||
Other1 | 35 (9.9%) | 55 (15.4%) | ||
COPD severity (investigator), N (%) | 352 | 358 | ||
Mild | 49 (13.9%) | 14 (3.9%) | ||
Moderate | 197 (56.0%) | 151 (42.2%) | ||
Severe | 100 (28.4%) | 152 (42.4%) | ||
Very severe | 6 (1.7%) | 41 (11.5%) | ||
COPD severity (GOLD 2006), N (%) | 137 | 323 | ||
Grade 1 (mild) | 31 (22.6%) | 16 (5.0%) | ||
Grade 2 (moderate) | 62 (45.3%) | 183 (56.6%) | ||
Grade 3 (severe) | 13 (9.5%) | 38 (11.8%) | ||
Grade 4 (very severe) | 31 (22.6%) | 86 (26.6%) | ||
COPD severity (GOLD 2011), N (%) 2 | 136 | 319 | ||
Group A: Low risk, less symptoms | 20 (14.7%) | 71 (22.3%) | ||
Group B: Low risk, more symptoms | 15 (11.0%) | 72 (22.6%) | ||
Group C: High risk, less symptoms | 45 (33.1%) | 52 (16.3%) | ||
Group D: High risk, more symptoms | 56 (41.2%) | 124 (38.9%) | ||
Median time in years since diagnosis (range) | 5.0 (0–40) | 347 | 4.0 (0–30) | 352 |
FEV 1 , mean (SD) 3 | ||||
% predicted | 60.5 (22.8) | 145 | 53.6 (16.7) | 334 |
Arterial blood gas (mmHg), mean (SD) | ||||
PaO2 | 72.4 (12.8) | 79 | 70.0 (11.7) | 221 |
PaCO2 | 42.1 (6.2) | 66 | 41.2 (6.0) | 218 |
Dyspnea (MRC grade), N (%) | 349 | 353 | ||
1 (strenuous exercise) | 58 (16.6%) | 24 (6.8%) | ||
2 (walking upstairs or uphill) | 146 (41.8%) | 114 (32.3%) | ||
3 (walking on the flat) | 96 (27.5%) | 103 (29.2%) | ||
4 (walking slowly) | 35 (10.0%) | 77 (21.8%) | ||
5 (daily activities) | 14 (4.0%) | 35 (9.9%) | ||
Chronic symptoms, N (%) 4 | ||||
Daily expectorations | 261 (74.6%) | 350 | 232 (65.4%) | 355 |
Daily cough | 307 (87.7%) | 350 | 287 (81.1%) | 354 |
Daily expectorations + cough | 245 (70.0%) | 350 | 224 (63.3%) | 354 |
Quality of life (CCQ) score, median 5 | 304 | 336 | ||
Symptoms | 3.3 | 2.8 | ||
Functional status | 2.5 | 2.3 | ||
Mental status | 2.0 | 2.0 | ||
Total | 2.7 | 2.4 | ||
History of repeated exacerbations, N (%) 6 | 222 (63.1%) | 352 | 106 (29.6%) | 358 |