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Table 3 Compliance of practice patterns with FSC marketing conditions for prescription according to prior ICS intake, irrespective of FEV 1 availability

From: Real-life use of fluticasone propionate/salmeterol in patients with chronic obstructive pulmonary disease: a French observational study

 

Patients with prior ICS

ICS-naïve patients

 

GPs (n = 159)

Pulmonologists (n = 120)

GPs (n = 193)

Pulmonologists (n = 238)

Approved prescription condition respected, N (%)

    

  FEV1 < 60% predicted1

53 (33.3%)

76 (63.3%)

28 (14.5%)

144 (60.5%)

  History of repeated exacerbations

109 (68.6%)

51 (42.5%)

113 (58.5%)

55 (23.1%)

  Continuous bronchodilator therapy

101 (63.5%)

97 (80.8%)

57 (29.5%)

89 (37.4%)

  All conditions respected (regulatory approval criteria)

25 (15.7%)

31 (25.8%)

6 (3.1%)

16 (6.7%)

Details of conditions respected, N (%)

    

  None

15 (9.4%)

6 (5.0%)

53 (27.5%)

47 (19.7%)

  FEV1 only

5 (3.1%)

5 (4.2%)

9 (4.7%)

69 (29.0%)

  Repeated exacerbations only

27 (17.0%)

2 (1.7%)

66 (34.2%)

13 (5.5%)

  Continuous bronchodilator only

18 (11.3%)

28 (23.3%)

13 (6.7%)

28 (11.8%)

  FEV1 and repeated exacerbations only

11 (6.9%)

10 (8.3%)

8 (4.1%)

20 (8.4%)

  FEV1 and bronchodilators only

12 (7.5%)

30 (25.0%)

5 (2.6%)

39 (16.4%)

  Repeated exacerbations and bronchodilators only

46 (28.9%)

8 (6.7%)

33 (17.1%)

6 (2.5%)

  FEV1 and repeated exacerbations +/− bronchodilators

36 (22.6%)

41 (34.2%)

14 (7.3%)

36 (15.1%)

  FEV1 or repeated exacerbations

126 (79.2%)

86 (71.7%)

127 (65.8%)

163 (68.5%)

N conditions respected, N (%)

    

  At least one

144 (90.6%)

114 (95.0%)

140 (72.5%)

191 (80.3%)

  At least two

94 (59.1%)

79 (65.8%)

52 (26.9%)

81 (34.0%)

  1. 1Missing FEV1 data were considered non-respect of condition.