Table 4 Associations between increasing age (5-year intervals) and female sex and the respiratory symptoms wheeze, asthma and rhinitis at baseline (odds ratios with 95% confidence intervals) in total baseline population, population at 10-yrs follow-up and population at 20-yrs follow-up, and differences between these groups given as ratios of odds ratios (with bootstrapped 95% confidence intervals) in population at 10-yrs follow-up over total baseline population, and in population at 20-yrs follow-up over total baseline population a
From: Longterm follow-up in European respiratory health studies – patterns and implications
Baseline population OR (95%CI) | 10-yrs follow-up population OR (95%CI) | Ratio of ORs (95%CI) b | 20-yrs follow-up population OR (95%CI) | Ratio of ORs (95%CI) b | |||
|---|---|---|---|---|---|---|---|
Wheeze | Age | RHINE | 1.00 (0.98, 1.02) | 1.01 (0.98, 1.03) | 1.01 (0.99, 1.02) | 0.98 (0.95, 1.02) | 0.98 (0.96, 1.01) |
Italian ECRHS | 1.10 (1.03, 1.17) | 1.10 (1.02, 1.19) | 1.00 (0.96, 1.05) | 1.15 (1.01, 1.31) | 1.05 (0.93, 1.18) | ||
ISAYA | 0.97 (0.91, 1.03) | 0.96 (0.88, 1.05) | 0.99 (0.94, 1.07) | - | - | ||
Sex | RHINE | 0.95 (0.90, 1.02) | 0.99 (0.92, 1.07) | 1.04 (1.00, 1.08) | 0.96 (0.87, 1.05) | 1.01 (0.94, 1.07) | |
Italian ECRHS | 0.76 (0.64, 0.90) | 0.74 (0.60, 0.91) | 0.97 (0.86, 1.10) | 0.63 (0.44, 0.91) | 0.83 (0.60, 1.15) | ||
ISAYA | 0.81 (0.69, 0.96) | 0.79 (0.62, 1.01) | 0.98 (0.82, 1.16) | - | - | ||
Asthma | Age | RHINE | 0.98 (0.93, 1.02) | 0.98 (0.93, 1.03) | 1.00 (0.97, 1.03) | 0.96 (0.90, 1.02) | 0.98 (0.94, 1.03) |
Italian ECRHS | 0.99 (0.90, 1.08) | 0.94 (0.84, 1.05) | 0.95 (0.89, 1.01) | 0.88 (0.71, 1.08) | 0.89 (0.73, 1.06) | ||
ISAYA | 0.92 (0.83, 1.02) | 0.95 (0.83, 1.09) | 1.03 (0.93, 1.15) | - | - | ||
Sex | RHINE | 1.16 (1.02, 1.32) | 1.21 (1.05, 1.40) | 1.04 (0.97, 1.13) | 1.13 (0.95, 1.35) | 0.97 (0.87, 1.11) | |
Italian ECRHS | 0.84 (0.66, 1.08) | 0.82 (0.60, 1.12) | 0.98 (0.80, 1.18) | 0.60 (0.34, 1.06) | 0.71 (0.41, 1.18) | ||
ISAYA | 1.08 (0.82, 1.41) | 0.94 (0.64, 1.38) | 0.87 (0.67, 1.16) | - | - | ||
Rhinitis | Age | RHINE | 0.97 (0.95, 0.99) | 0.97 (0.95, 1.00) | 1.00 (0.99, 1.02) | 0.97 (0.94, 1.00) | 1.00 (0.98, 1.02) |
Italian ECRHS | 0.94 (0.89, 0.99) | 0.93 (0.88, 0.99) | 0.99 (0.96, 1.03) | 0.91 (0.83, 1.01) | 0.97 (0.89, 1.07) | ||
ISAYA | 0.93 (0.88, 0.98) | 0.91 (0.84, 0.98) | 0.98 (0.93, 1.03) | - | - | ||
Sex | RHINE | 0.99 (0.92, 1.05) | 1.01 (0.93, 1.09) | 1.02 (0.98, 1.06) | 1.01 (0.92, 1.11) | 1.02 (0.96, 1.09) | |
Italian ECRHS | 0.93 (0.81, 1.07) | 0.89 (0.75, 1.06) | 0.96 (0.86, 1.06) | 0.73 (0.55, 0.97) | 0.78 (0.61, 1.01) | ||
ISAYA | 0.85 (0.74, 0.99) | 0.79 (0.64, 0.97) | 0.93 (0.81, 1.06) | - | - |