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Table 4 Correlation of clinical and functional variables with VO 2 peak in CF patients

From: Determinants of exercise capacity in cystic fibrosis patients with mild-to-moderate lung disease

Qualitative variables

n

 

Pvalue

  Female

102

 

.22

  ∆F508 homozygous mutation

79

 

.02

  Exocrine pancreatic insufficiency

102

 

.55

  Pseudomonas aeruginosa

99

 

.36

Quantitative variables

n

Correlation (r)

  Age, years

102

−0.11

.29

  BMI, kg/m2*

102

0.26

.009

  Leukocytosis, 109/mm3

70

−0.42

.0003

  CRP, mg/L

64

−0.34

.006

  Serum albumin, g/L

43

0.34

.02

  FEV1 a*

102

0.71

< .0001

  FVCa*

102

0.69

< .0001

  RVa

79

−0.58

< .0001

  DLCOa

68

0.56

< .0001

  PaO2, mm Hg

98

0.43

< .0001

  PaCO2, mm Hg

98

0.11

.29

Cardiopulmonary exercise parameters

n

Correlation (r)

  VE peak, L

102

0.64

< .0001

  VE/VCO2 peak*

98

−0.35

< .0001

  BR, %*

102

0.37

.0001

  VD/VT peak*

96

−0.64

< .0001

  PaCO2 peak, mm Hg*

97

−0.45

< .0001

  P(A-a)O2 peak, mm Hg*

97

−0.54

< .0001

  Lactatemia peak, mmol/L*

86

0.59

< .0001

  HR peaka

102

0.40

< .0001

  1. aCorrelations based on percentage of predicted values.
  2. *Selected variables for multivariate stepwise analysis.