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Table 4 Correlation of clinical and functional variables with VO 2 peak in CF patients

From: Determinants of exercise capacity in cystic fibrosis patients with mild-to-moderate lung disease

Qualitative variables n   Pvalue
  Female 102   .22
  ∆F508 homozygous mutation 79   .02
  Exocrine pancreatic insufficiency 102   .55
  Pseudomonas aeruginosa 99   .36
Quantitative variables n Correlation (r)
  Age, years 102 −0.11 .29
  BMI, kg/m2* 102 0.26 .009
  Leukocytosis, 109/mm3 70 −0.42 .0003
  CRP, mg/L 64 −0.34 .006
  Serum albumin, g/L 43 0.34 .02
  FEV1 a* 102 0.71 < .0001
  FVCa* 102 0.69 < .0001
  RVa 79 −0.58 < .0001
  DLCOa 68 0.56 < .0001
  PaO2, mm Hg 98 0.43 < .0001
  PaCO2, mm Hg 98 0.11 .29
Cardiopulmonary exercise parameters n Correlation (r)
  VE peak, L 102 0.64 < .0001
  VE/VCO2 peak* 98 −0.35 < .0001
  BR, %* 102 0.37 .0001
  VD/VT peak* 96 −0.64 < .0001
  PaCO2 peak, mm Hg* 97 −0.45 < .0001
  P(A-a)O2 peak, mm Hg* 97 −0.54 < .0001
  Lactatemia peak, mmol/L* 86 0.59 < .0001
  HR peaka 102 0.40 < .0001
  1. aCorrelations based on percentage of predicted values.
  2. *Selected variables for multivariate stepwise analysis.