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Table 1 Respiragene study in Auckland NZ (n = 43)

From: Genetic test to stop smoking (GeTSS) trial protocol: randomised controlled trial of a genetic test (Respiragene) and Auckland formula to assess lung cancer risk

 

Cancer susceptibility scale (compared with normal lifetime risk)

Cancer susceptibility score

Estimated lifetime risk of lung cancer

Initial intention to quit

Proportion that stopped smoking at 2-4 weeks

Proportion still not smoking at 6 months

Expected result for telephone counselling (Figure 2)

-

-

15%

41%

10-20%

9-12%

Telephone counselling + Respiragene test

1-2.3 (10-35% risk) 2.3-6.7 (35-65% risk) 6.7-8 (65%-80% risk)

27 had average risk score

15%

67%

8/27 (30%)

8 (30%)

16 had high or very high risk score

30-50% (4-10 times average risk)

89%

10/16 (63%)

6 (37.5%)

  1. Smoking cessation after Respiragene testing and estimation of lung cancer risk with telephone counselling in a small pilot study in Auckland NZ (n = 43) compared with expected quit rate.