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Table 2 Clinical and serological characteristics of included patients (nominal variables)

From: Dynamics of soluble and cellular inflammatory markers in nasal lavage obtained from Cystic Fibrosis patients during intravenous antibiotic treatment

Nominal variables

n

Absolute frequency

Gender (f/m)

17

10 (53.3%)/7 (47.7%)

Body Mass Index (BMI) scoring*1

17

3 (17.7%)/3 (17.7) /11 (64.7%)/0 (0%)

Severe under-/under-/normal-/overweight

Pancreatic insufficiency

17

13 (76.5%)

Diabetes mellitus

17

6 (35%)

Allergy

17

10 (59.0%)

Chronic rhinosinusitis (CRS)

17

11 (65%)

EPOS criteria for CRS at inclusion [28]:

No

Acute remittent

Chronic

  Nasal blockage or obstruction or congestion

3 (17.6%)

2 (11.8%)

12 (70.6%)

  Anterior or posterior nasal drip

2 (11.8%)

4 (23.5%)

11 (64.7%)

  Facial pain or pressure

15 (88.2%)

1 (5.9%)

1 (5.9%)

  Reduction or loss of smell

12 (70.6%)

0

4 (23.5%)

Allergic rhinitis

17

7 (41%)

Allergic Bronchopulmonary Aspergillosis (ABPA)

17

2 (11.8%)

History of nasal surgery

17

6 (35%)

Therapy

17

 

  Current azithromycin

13 (77%)

  Current steroids nasal

4 (24%)

  Recombinant DNase

8 (47%)

  i.v. ABs (twice per day, mg/kg):

 

    Ceftazidim (200)/tobramycin (10)

11 (65%)

    Tobramycin (10)/meropenem (100)

5 (29%)

    Ceftazidim (200)/tobramycin (10)/meropenem (100)

1 (5.9%)

Permanent colonisation LAW with*2:

 

15 (88%)

  P. aeruginosa (mucoid)

17

13 (76.5%)

  P. aeruginosa (non-mucoid)

 

4 (23.5%)

  S. aureus

 

7 (41%)

Permanent/intermittent colonisation UAW with*3:

 

7 (41.2%)/5 (29.4%)

  P. aeruginosa (mucoid)

 

7 (41.2%)

  P. aeruginosa (non-mucoid)

 

13 (76.5%)

  S. aureus

 

3 (17.7%)/ 4 (23.5%)

P. aeruginosa serum antibody positive:

15

 

  Alcaline protease

3 (20%)

  Elastase

6 (40%)

  Exotoxine A

4 (27%)

  1. *1: SDSLMS: Standard-Deviation-Score; L = Box cox-power transformation, M = median, S = variation coefficient.
  2. *1: BMI scoring was carried out according to [33].
  3. *2: Permanent and intermittent colonisation was stated using the criteria published by Lee et al. [31], where the authors define a chronic colonisation if more than 50% of cultures within the last year were found to be positive and intermittent if less than 50% of cultures within the last year were found to be positive.