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Table 2 Comparison between idiopathic pleuroparenchymal fibroelastosis (IPPFE) and idiopathic pulmonary fibrosis (IPF): laboratory, physiologic, and bronchoalveolar lavage data

From: Quantitative analysis of lung elastic fibers in idiopathic pleuroparenchymal fibroelastosis (IPPFE): comparison of clinical, radiological, and pathological findings with those of idiopathic pulmonary fibrosis (IPF)

  IPPFE (n = 6) IPF (n = 28) p value
Laboratory findings    
 Serum LDH, U/L 192 ± 37 223 ± 43 0.106
 Serum KL-6, U/ml 755 ± 473 1282 ± 888 0.199
 Serum SP-D, ng/ml 298 ± 346 222 ± 136 0.527
 SP-D/KL-6 0.38 ± 0.20 0.26 ± 0.18 0.168
Physiologic    
 Resting PaO2, mm Hg 77.6 ± 11.5 83.2 ± 11.0 0.363
 Resting PaCO2, mm Hg 43.5 ± 7.2 40.6 ± 3.1 0.138
 FVC, L 1.97 ± 0.42 2.91 ± 0.91 0.021
 FVC, % predicted 62.7 ± 10.9 88.6 ± 21.9 0.009
 DLCO, % predicted 77.9 ± 13.4 89.0 ± 26.1 0.395
 ΔFVC in 12 mo, L -0.51 ± 0.35 -0.32 ± 0.38 0.364
BAL fluid cell analysis    
 Lymphocytes, % 6.0 ± 4.5 5.2 ± 7.0 0.782
 Neutrophils, % 2.5 ± 3.3 0.6 ± 0.8 0.018
 Eosinophils, % 1.7 ± 2.0 0.4 ± 0.6 0.011
  1. Data are presented as mean ± SD.
  2. Data are analysed with Student’s t-test.
  3. Definition of abbreviations: FVC forced vital capacity, FEV1 forced expiratory volume in 1 second, DLCO diffusion lung capacity for carbon monoxide, BAL bronchoalveolar lavage.