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Table 2 Comparison between idiopathic pleuroparenchymal fibroelastosis (IPPFE) and idiopathic pulmonary fibrosis (IPF): laboratory, physiologic, and bronchoalveolar lavage data

From: Quantitative analysis of lung elastic fibers in idiopathic pleuroparenchymal fibroelastosis (IPPFE): comparison of clinical, radiological, and pathological findings with those of idiopathic pulmonary fibrosis (IPF)

 

IPPFE (n = 6)

IPF (n = 28)

p value

Laboratory findings

   

 Serum LDH, U/L

192 ± 37

223 ± 43

0.106

 Serum KL-6, U/ml

755 ± 473

1282 ± 888

0.199

 Serum SP-D, ng/ml

298 ± 346

222 ± 136

0.527

 SP-D/KL-6

0.38 ± 0.20

0.26 ± 0.18

0.168

Physiologic

   

 Resting PaO2, mm Hg

77.6 ± 11.5

83.2 ± 11.0

0.363

 Resting PaCO2, mm Hg

43.5 ± 7.2

40.6 ± 3.1

0.138

 FVC, L

1.97 ± 0.42

2.91 ± 0.91

0.021

 FVC, % predicted

62.7 ± 10.9

88.6 ± 21.9

0.009

 DLCO, % predicted

77.9 ± 13.4

89.0 ± 26.1

0.395

 ΔFVC in 12 mo, L

-0.51 ± 0.35

-0.32 ± 0.38

0.364

BAL fluid cell analysis

   

 Lymphocytes, %

6.0 ± 4.5

5.2 ± 7.0

0.782

 Neutrophils, %

2.5 ± 3.3

0.6 ± 0.8

0.018

 Eosinophils, %

1.7 ± 2.0

0.4 ± 0.6

0.011

  1. Data are presented as mean ± SD.
  2. Data are analysed with Student’s t-test.
  3. Definition of abbreviations: FVC forced vital capacity, FEV1 forced expiratory volume in 1 second, DLCO diffusion lung capacity for carbon monoxide, BAL bronchoalveolar lavage.
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BMC Pulmonary Medicine

ISSN: 1471-2466

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