|
Characteristic
|
Visit 1 (n = 103)
|
Visit 2†(n = 98)
|
p-value
|
|---|
|
Female, n (%)
|
47 (45.6)
|
45 (45.9)
|
NS
|
|
Age, yrs
|
33.1 ± 0.9
|
33.2 ± 0.9
|
NS
|
|
Body mass index
|
21.6 ± 0.3
|
21.4 ± 0.2
|
NS
|
|
Nonsmokers, n (%)
|
81 (78.6)
|
NA
| |
|
Ex-smokers, n (%)
|
22 (21.4)
|
NA
| |
|
Atopic by skin prick, n (%)
|
69 (67.0)
|
NA
| |
|
Total IgE, kU/L
|
631.7 ± 94.1
|
568.4 ± 86.8
|
NS
|
|
Eosinophil in WBC%
|
5.4 ± 0.4
|
4.0 ± 0.3
|
< 0.001
|
|
FEV1/FVC, %
|
72.1 ± 0.6
|
74.9 ± 0.8
|
0.0026
|
|
FEV1, % predicted
|
84.1 ± 1.4
|
87.8 ± 0.9
|
0.0270
|
|
≥80%, n (%)
|
72 (69.9)
|
85 (86.7)
| |
|
60-79%, n (%)
|
20 (19.4)
|
10 (10.2)
| |
|
< 60%, n (%)
|
11 (10.7)
|
3 (3.1)
| |
|
YKL-40, ng/ml
|
75.2 (55.8-86.8)
|
54.5 (46.4-58.4)
|
< 0.001
|
|
AQLQ
|
5.19 ± 0.11
|
5.35 ± 0.10
|
NS
|
|
ACT score
|
20.6 ± 0.5
|
22.1 ± 0.3
|
0.0101
|
|
25, n (%)
|
26 (25.2)
|
31 (31.6)
| |
|
20-24, n (%)
|
52 (50.5)
|
60 (61.3)
| |
|
5-19, n (%)
|
25 (24.3)
|
7 (7.1)
| |
- Data are presented as mean ± SEM or n (%), except for YKL-40, median (IQR).
- Note: FEV1, forced expiratory volume in one second; FVC, forced vital capacity; AQLQ, Asthma Quality of Life Questionnaire; ACT, asthma control test; NS, not significant; NA, not assessed.
- †Five patients were dropped out.
