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Table 1 Characteristic of the study participants

From: YKL-40 is correlated with FEV1 and the asthma control test (ACT) in asthmatic patients: influence of treatment

Characteristic

Visit 1 (n = 103)

Visit 2(n = 98)

p-value

Female, n (%)

47 (45.6)

45 (45.9)

NS

Age, yrs

33.1 ± 0.9

33.2 ± 0.9

NS

Body mass index

21.6 ± 0.3

21.4 ± 0.2

NS

Nonsmokers, n (%)

81 (78.6)

NA

 

Ex-smokers, n (%)

22 (21.4)

NA

 

Atopic by skin prick, n (%)

69 (67.0)

NA

 

Total IgE, kU/L

631.7 ± 94.1

568.4 ± 86.8

NS

Eosinophil in WBC%

5.4 ± 0.4

4.0 ± 0.3

< 0.001

FEV1/FVC, %

72.1 ± 0.6

74.9 ± 0.8

0.0026

FEV1, % predicted

84.1 ± 1.4

87.8 ± 0.9

0.0270

 ≥80%, n (%)

72 (69.9)

85 (86.7)

 

 60-79%, n (%)

20 (19.4)

10 (10.2)

 

 < 60%, n (%)

11 (10.7)

3 (3.1)

 

YKL-40, ng/ml

75.2 (55.8-86.8)

54.5 (46.4-58.4)

< 0.001

AQLQ

5.19 ± 0.11

5.35 ± 0.10

NS

ACT score

20.6 ± 0.5

22.1 ± 0.3

0.0101

 25, n (%)

26 (25.2)

31 (31.6)

 

 20-24, n (%)

52 (50.5)

60 (61.3)

 

 5-19, n (%)

25 (24.3)

7 (7.1)

 
  1. Data are presented as mean ± SEM or n (%), except for YKL-40, median (IQR).
  2. Note: FEV1, forced expiratory volume in one second; FVC, forced vital capacity; AQLQ, Asthma Quality of Life Questionnaire; ACT, asthma control test; NS, not significant; NA, not assessed.
  3. Five patients were dropped out.