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Table 1 Characteristic of the study participants

From: YKL-40 is correlated with FEV1 and the asthma control test (ACT) in asthmatic patients: influence of treatment

Characteristic Visit 1 (n = 103) Visit 2(n = 98) p-value
Female, n (%) 47 (45.6) 45 (45.9) NS
Age, yrs 33.1 ± 0.9 33.2 ± 0.9 NS
Body mass index 21.6 ± 0.3 21.4 ± 0.2 NS
Nonsmokers, n (%) 81 (78.6) NA  
Ex-smokers, n (%) 22 (21.4) NA  
Atopic by skin prick, n (%) 69 (67.0) NA  
Total IgE, kU/L 631.7 ± 94.1 568.4 ± 86.8 NS
Eosinophil in WBC% 5.4 ± 0.4 4.0 ± 0.3 < 0.001
FEV1/FVC, % 72.1 ± 0.6 74.9 ± 0.8 0.0026
FEV1, % predicted 84.1 ± 1.4 87.8 ± 0.9 0.0270
 ≥80%, n (%) 72 (69.9) 85 (86.7)  
 60-79%, n (%) 20 (19.4) 10 (10.2)  
 < 60%, n (%) 11 (10.7) 3 (3.1)  
YKL-40, ng/ml 75.2 (55.8-86.8) 54.5 (46.4-58.4) < 0.001
AQLQ 5.19 ± 0.11 5.35 ± 0.10 NS
ACT score 20.6 ± 0.5 22.1 ± 0.3 0.0101
 25, n (%) 26 (25.2) 31 (31.6)  
 20-24, n (%) 52 (50.5) 60 (61.3)  
 5-19, n (%) 25 (24.3) 7 (7.1)  
  1. Data are presented as mean ± SEM or n (%), except for YKL-40, median (IQR).
  2. Note: FEV1, forced expiratory volume in one second; FVC, forced vital capacity; AQLQ, Asthma Quality of Life Questionnaire; ACT, asthma control test; NS, not significant; NA, not assessed.
  3. Five patients were dropped out.