Table 2 Comparison of the methods described in the text in terms of threshold dose (sensitivity) and dose-response ratio (reactivity), stratified according to BHR status. NS: p value not statistically significance between the two methods. The greater reactivity of the interrupter method is shown.
From: Use of interrupter technique in assessment of bronchial responsiveness in normal subjects
Methods (× ± SD) | |||
|---|---|---|---|
Subjects showing BHR | |||
PD100Rint, EI (mgs) | 0.57 ± 0.20 | Dose-response ratio (%/mg) | 690 ± 390 |
PD20FEV1 (mgs) | 0.72 ± 0.66 | Dose-response ratio (%mg) | 98 ± 90 |
NS | P < 0.05 | ||
Subjects with normal measurable reactions (> 0.8 mgs) | |||
PD100Rint, EI (mgs) | 3.42 ± 3.10 | Dose-response ratio (%/mg) | 74.86 ± 49.87 |
PD20FEV1 (mgs) | 3.13 ± 2.65 | Dose-response ratio (%/mg) | 20 ± 3.82 |
NS | P < 0.05 | ||