Table 2 Clinical characteristics of the 201 families (867 participants) that also include non-affected siblings of the core families. Descriptors of categorical variables include n/total sample in the first row and percent in the second row. Descriptors of continuous variables include mean values in the first row and standard deviation in the second row.
From: Phenotypic and genetic heterogeneity in a genome-wide linkage study of asthma families
Parents | Children | |||
|---|---|---|---|---|
Stage 1 | Stage 2 | Stage 1 | Stage 2 | |
sex females | 97/194 50.0% | 104/208 50.0% | 96/221 43.4% | 114/244 46.7% |
Asthma diagnosis | 33/194 17.0% | 60/208 28.8% | 200/221 90.5% | 213/244 87.3% |
D.pter skin > = 3 mm | 68/193 35.2% | 58/206 28.2% | 111/217 51.2% | 107/242 44.2% |
D.far skin > = 3 mm | 57/193 29.5% | 48/207 23.2% | 101/217 46.5% | 88/242 36.4% |
D.pter. CAP class >1 | 51/183 27.9% | 43/147 29.3% | 124/217 57.1% | 102/198 51.5% |
D.far. CAP class >1 | 46/183 25.1% | 39/147 26.5% | 122/217 56.2% | 100/198 50.5% |
age (years) | 39.8 +/-5.7 | 40.9 +/-5.5 | 11.0 +/-4.2 | 10.8 +/-3.4 |
onset asthma (years) | not reliable | not reliable | 3.8 +/-2.8 | 4.3 +/-3.1 |
height (cm) | 172.3 +/-9.0 | 172.3 +/- 9.9 | 146.9 +/-19.2 | 156.3 +/-18.1 |
weight (kg) | 76.0 +/-14.9 | 78.0 +/-16.6 | 41.5 +/-17.0 | 47.4 +/-16.6 |
ln(Ige) (kU/L) | 4.1 +/-1.7 | 4.1 +/-1.6 | 5.0 +/-2.0 | 5.0 +/-1.8 |
ln(eosinophil) (count / mm3) | 0.3 +/-1.7 | 0.7 +/-1.5 | 1.1 +/-1.6 | 1.1 +/-1.6 |
FEV1 (ml) | 3.594 +/-804 | 3.464 +/- 957 | 2.312 +/-883 | 2.861 +/-1.061 |