Table 6 Multivariate Coefficients for Rate of loss of best FVC (after allowance for regression to the mean)
From: The Darlington and Northallerton Long Term Asthma Study: pulmonary function
Age Excluded | Age Included | ||||
|---|---|---|---|---|---|
Coefficient (sd) | p | Coefficient (sd) | p | ||
Gender (male v female) | 10.8 (5.6) | 0.05 | 11.4 (5.6) | 0.04 | |
Asthma since childhood | 16.0 + (6.0) | 0.007 | 4.7+ (6.9) | 0.49 | |
Social Classes 1 & 2 (v. classes 4 & 5) | 10.7 (6.4) | 0.13 | 7.5 (6.4) | 0.29 | |
Social Class 3 (v. classes 4 & 5) | 0.2+ (6.0) | 1.4+ (5.9) | |||
Amount smoked (per 10 pack years) | 1.9 (1.4) | 0.18 | 0.9 (1.4) | 0.52 | |
Best PEF(per 10% deficit) | 0.6+ (1,.4) | 0.65 | 0.6+ (1.9) | 0.67 | |
Actual/Best PEF(10% deficit) | 1.3 (1.8) | 0.47 | 0.1 (1.9) | 0.94 | |
Age at entry (per decade) (difference from age 50) | Linear | 2.1+ (3.7) | |||
quadratic | 4.0+ (1.0) | ||||
cubic | 1.4 (0.6) | 0.02 | |||
Duration of asthma at entry (per decade) (difference from duration 20 yrs) | Linear | 4.0 (2.8) | 0.8 (2.8) | ||
quadratic | 5.2 (1.7) | 3.2 (1.8) | |||
cubic | 1.46 + (0.44) | 0.001 | 0.97 + (0.46) | 0.03 | |