Table 2 Plasma levels of serine protease inhibitors in older healthy (asymptomatic) and COPD subjects with and without severe Z AAT deficiency.

AAT-variant

N

AAT (mg/ml)

N

ACT (mg/ml)

N

SLPI (ng/ml)

Mean* ± SD

Mean* ± SD

Mean* ± SD

ZZ

10

0.20 ± 0.03

10

0.40 ± 0.20

9

44.0 ± 15

MM

20

1.37 ± 0.20

15

0.37 ± 0.15

13

38.2 ± 9.9

COPD subjects (B)

AAT-variant

N

AAT (mg/ml)

N

ACT (mg/ml)

N

SLPI (ng/ml)

Mean* ± SD

Mean* ± SD

Mean* ± SD

ZZ

10

0.32 ± 0.17

10

0.42 ± 0.12

10

48.5 ± 8.4

MM

10

1.73 ± 0.22

9

0.62 ± 0.21

9

51.1 ± 6.1