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Table 3 The Relationship Between Lung function and Serum Protein Biomarkers at baseline

From: Circulating surfactant protein D as a potential lung-specific biomarker of health outcomes in COPD: a pilot study

  Baseline SPD* Baseline CC16* Baseline CRP*
  β R P value β R P value β R P value
Baseline FEV1 -0.204 0.42 0.045 -0.057 0.09 0.675 0.031 0.13 0.549
Baseline SPD*   -- -- -0.293 0.23 0.295 0.080 0.17 0.446
Baseline CC16*   -- --   -- -- -0.059 0.16 0.473
  1. * Logarithmic scale.
  2. A negative β-coefficient indicates an inverse relationship; whereas a positive β-coefficient indicates a positive linear relationship between the two variables.
  3. Abbreviations : CC16 – Clara cell protein-16, CRP – C-reactive protein, FEV1 – forced expiratory volume in one second, SPD – surfactant protein D.