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Table 1 Data for evolving ALI series

From: Hypertonic saline reduces inflammation and enhances the resolution of oleic acid induced acute lung injury

Variable

Hypertonic Saline (n = 6)

Control (n = 6)

Animal Weight (g)

354 ± 10.0

336 ± 5.3

Mean Arterial Pressure (mmHg)

  

   0 min

144 ± 12.0

140 ± 7.4

   10 min

167 ± 7.4

149 ± 7.6

   20 min

158 ± 8.7

148 ± 7.8

Peak Airway Pressure (mmHg)

  

   0 min

5.4 ± 0.6

5.7 ± 0.2

   10 min

5.3 ± 0.5

5.7 ± 0.2

   20 min

6.1 ± 0.6

6.5 ± 0.2

Arterial PO2

  

   FiO2 0.3

11.9 ± 0.5

12.0 ± 0.5

   FiO2 1.0

72.0 ± 1.5

71.7 ± 2.1

Alveolar-arterial O2 Gradient (mmHg)

  

   FiO2 = 0.21

11.9 ± 1.00

10.9 ± 0.56

   FiO2 = 1.0

21.8 ± 4.94

17.3 ± 2.25

Static Lung Compliance (ml.mmHg-1)

0.43 ± 0.02

0.44 ± 0.02

BAL Protein concentration (mg/L)

4559 ± 418

5398 ± 522

  1. Notes: Data are expressed as mean ± SEM.
  2. *Significantly different from Hypertonic Saline (P < 0.02, ANOVA).