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Table 2 Data for resolving ALI series

From: Hypertonic saline reduces inflammation and enhances the resolution of oleic acid induced acute lung injury

Variable

Hypertonic Saline (n = 12)

Control (n = 12)

Animal Weight (g)

330 ± 6.5

334 ± 5.5

Mean Arterial Pressure (mmHg)

  

   0 min

141 ± 9.0

119 ± 8.9

   10 min

160 ± 7.3

150 ± 5.8

   20 min

150 ± 7.8

142 ± 7.5

Peak Airway Pressure (mmHg)

  

   0 min

4.8 ± 0.3

5.2 ± 0.2

   10 min

4.7 ± 0.3

4.9 ± 0.1

   20 min

5.1 ± 0.3

5.3 ± 0.2

Arterial PO2

  

   FiO2 0.3

12.2 ± 0.6

11.9 ± 0.6

   FiO2 1.0

71.0 ± 0.9

68.3 ± 2.0

Alveolar-arterial O2 Gradient (mmHg)

  

   FiO2 = 0.21

10.8 ± 0.5

11.0 ± 0.6

   FiO2 = 1.0

18.7 ± 0.9

22.0 ± 2.0

Static Lung Compliance (ml.mmHg-1)

0.55 ± 0.04

0.44 ± 0.04

BAL Protein concentration (mg/L)

2595 ± 640

3888 ± 564

  1. Data are expressed as mean ± SEM.
  2. *Significantly different from Hypertonic Saline (P < 0.05, ANOVA).