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Table 2 Median levels of promising analytes as measured with the 29-plex assay

From: Host markers in Quantiferon supernatants differentiate active TB from latent TB infection: preliminary report

Analyte All subjects
(n = 19)
Active TB cases
(n = 10)
LTBI
(n = 9)
p-value
(Active TB vs LTBI)
EGF Nil 73.0
(23.4–148.9)
106.2
(40.8–148.9
51.4
(23.4–141.3
0.02
IFN-γ Ag-Nil 99.1
(0.0–1265.0)
57.0
(0.0–646.3)
127.6
(38.6–1265.5)
0.08
IP-10* Ag-Nil 18139.0
(5313.0–>20000.0)
14446.0
(5313.0–>20000.0)
18224.0
(12470.0–>20000.0)
0.27
IL-2* Ag-Nil 160.0
(10.2–1778.0)
106.6
(10.2–640.9)
164.0
(57.8–1778.0)
0.19
IL-1α Ag-Nil 76.6
(0.0–235.4)
118.0
(0.0–235.4)
23.3
(0.0–158.5)
0.04
MIP-1β Ag-Nil 1770
(0.0–7847.0)
1210.0
(0.0–4098.0)
3220
(960.8–7847.0)
0.06
TNF-α Nil 50.8
(7.3–633.7)
94.9
(19.8–633.7)
15.9
(7.3–293.6)
0.01
TGF-α Nil 13.3
(0.0–230.1)
28.5
(0.0–230.1)
6.2
(0.0–13.3)
<0.01
VEGF Ag-Nil 0.0
(0.0–77.3)
0.0
(0.0–31.8)
36.3
(0.0–77.3)
<0.01
sCD40L Nil 869.0
(245.2–9852.0)
1388.0
(455.4–4038.0)
599.4
(245.2–9852.0)
0.03
sCD40L Ag-Nil 0.0
(0.0–9944.0)
0.0
(0.0–4.6)
309.4
(12.2–9944.0)
<0.01
  1. Median levels (pg/ml) and ranges (in parenthesis) of analytes with significant or near significant differences between TB cases and the latently infected individuals obtained with the 29-plex assay. * Marker was not included in the customized 8-plex kit. Levels shown as >20000 pg/ml were above the highest point on the standard curve.