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Table 1 Characteristics of severe and non-severe asthmatics in two subpopulations of patients in whom SCF and c-kit serum levels were determined (* p < 0,05)

From: Stem cell factor and its soluble receptor (c-kit) in serum of asthmatic patients- correlation with disease severity

  SCF group (n = 88) Sc-kit group (n = 63)
  Non-severe asthma Severe asthma Non-severe asthma Severe asthma
Number of patients 32 56 22 41
Female/male 15/17 41/15 14/8 30/11
Age mean (range) 39,9 (19–57) 51 (23–74) 41 (24–64) 49,3 (22–74)
Patients with positive SPT 28 (87%) 39 (69%) 17 27
Aspirin hypersensitivity 15 (47%) 27 (48%) 5 18
Nasal polyps 13 (40%) 18 (32%) 4 10
FEV1% of predictive value (mean) 97% 73%* 98% 75%
Patients on inhaled GCS (n) 32 56 22 41
-mean daily dose
(mcg of budesonide)
612 1990* 540 2035*
Patients on oral GCS 0 33* 0 22*
-mean daily dose
(mg of prednisone)
0 7,79* 0 3,8*
Total IgE (kU/ml) 322,4 +/- 87 317,9 +/- 62 302,3+/- 57 335,9 +/- 92
ECP (μg/ml) 8,4 +/- 1,76 12,92 +/- 1,45 10,16 +/- 1,26 12,21 +/- 1,97
Eosinophil count (cells/μl) 266 +/- 62 351,4 +/- 36,5 290,8 +/- 46,5 313,8 +/- 40,25