From: Association of the TLR4 Asp299Gly polymorphism with lung function in relation to body mass index
Sex | Smoking Status# | TLR4 299# | ||||
---|---|---|---|---|---|---|
Male (n = 754) | Female (n = 971) | Never Smoker (n = 937) | Ever Smoker (n = 788) | Wild type (n = 1490) | Polymorphic (n = 235) | |
Observed FEV 1 (L) | 3.78 ± 0.03 | 2.65 ± 0.02 | 3.21 ± 0.03 | 3.18 ± 0.03 | 3.18 ± 0.02 | 3.31 ± 0.06+ |
% predicted | 98.44 ± 0.59 | 102.86 ± 0.54 | 102.47 ± 0.53 | 99.09 ± 0.60& | 100.91 ± 0.43 | 101.01 ± 1.05 |
Observed FVC (L) | 4.73 ± 0.04 | 3.39 ± 0.02 | 3.97 ± 0.04 | 3.98 ± 0.04 | 3.95 ± 0.03 | 4.14 ± 0.07+ |
% predicted | 98.55 ± 0.55 | 103.24 ± 0.51 | 102.38 ± 0.50 | 99.77 ± 0.57& | 101.10 ± 0.41 | 101.76 ± 0.97 |
Observed FEV 1 /FVC | 0.80 ± 0.002 | 0.81 ± 0.002 | 0.81 ± 0.0.002 | 0.80 ± 0.0.002& | 0.80 ± 0.002 | 0.80 ± 0.004 |
% predicted | 99.96 ± 0.29 | 100.06 ± 0.25 | 100.39 ± 0.26 | 99.57 ± 0.27& | 100.11 ± 0.20 | 99.44 ± 0.49 |
Observed FEF 25-75 (L/s) | 3.82 ± 0.05 | 2.89 ± 0.03 | 3.36 ± 0.04 | 3.21 ± 0.04& | 3.28 ± 0.03 | 3.37 ± 0.08 |
% predicted | 101.28 ± 1.10 | 103.89 ± 1.06 | 105.64 ± 1.04 | 99.30 ± 1.13& | 102.89 ± 0.82 | 101.80 ± 2.17 |