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Table 2 Observed mean value ± standard error and mean values of the % predicted ± standard error for the pulmonary function test variables for sex, smoking status and TLR4 Asp299Gly

From: Association of the TLR4 Asp299Gly polymorphism with lung function in relation to body mass index

  Sex Smoking Status# TLR4 299#
  Male (n = 754) Female (n = 971) Never Smoker
(n = 937)
Ever Smoker
(n = 788)
Wild type (n = 1490) Polymorphic
(n = 235)
Observed FEV 1 (L) 3.78 ± 0.03 2.65 ± 0.02 3.21 ± 0.03 3.18 ± 0.03 3.18 ± 0.02 3.31 ± 0.06+
   % predicted 98.44 ± 0.59 102.86 ± 0.54 102.47 ± 0.53 99.09 ± 0.60& 100.91 ± 0.43 101.01 ± 1.05
Observed FVC (L) 4.73 ± 0.04 3.39 ± 0.02 3.97 ± 0.04 3.98 ± 0.04 3.95 ± 0.03 4.14 ± 0.07+
   % predicted 98.55 ± 0.55 103.24 ± 0.51 102.38 ± 0.50 99.77 ± 0.57& 101.10 ± 0.41 101.76 ± 0.97
Observed FEV 1 /FVC 0.80 ± 0.002 0.81 ± 0.002 0.81 ± 0.0.002 0.80 ± 0.0.002& 0.80 ± 0.002 0.80 ± 0.004
   % predicted 99.96 ± 0.29 100.06 ± 0.25 100.39 ± 0.26 99.57 ± 0.27& 100.11 ± 0.20 99.44 ± 0.49
Observed FEF 25-75 (L/s) 3.82 ± 0.05 2.89 ± 0.03 3.36 ± 0.04 3.21 ± 0.04& 3.28 ± 0.03 3.37 ± 0.08
   % predicted 101.28 ± 1.10 103.89 ± 1.06 105.64 ± 1.04 99.30 ± 1.13& 102.89 ± 0.82 101.80 ± 2.17
  1. Note: Predicted values are adjusted for age and height.
  2. * Comparison made between Male and Female p value < 0.05
  3. ** Comparison made between Male and Female p value < 0.10
  4. + Comparison made between wild type and polymorphic group p value < 0.05
  5. &Comparison made between never smoker and ever smoker group p value < 0.05
  6. # Separate prediction equations used for males and females.